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Table 4 MDR models of gene-gene interactions between three SNPs

From: Interaction between COX-1 and COX-2 increases susceptibility to ischemic stroke in a Chinese population

SNPISLAA
Best candidate modelTraining accuracyTesting accuracyCVCPermutation test P valueBest candidate modelTraining accuracyTesting accuracyCVCPermutation test P value
1SNP30.52160.49817 /100.206SNP30.53420.534210/100.4270
2SNP1
SNP3
0.53750.521110 /100.300SNP1
SNP3
0.55040.534610/100.8400
3SNP1
SNP2
SNP3
0.54450.517610 /100.330SNP1
SNP2
SNP3
0.55910.518510/100.5600
SNPCESSVO
Best candidate modelTraining accuracyTesting accuracyCVCPermutation test P valueBest candidate modelTraining accuracyTesting accuracyCVCPermutation test P value
1SNP10.52280.48345/100.7600–0.7610SNP10.530.5310 /100.8520
2SNP1
SNP3
0.53830.477610/100.9510SNP1
SNP3
0.54280.530410 /100.0050–0.0060
3SNP1
SNP2 SNP3
0.55520.459210/100.7990–0.8000SNP1
SNP2 SNP3
0.54960.512510 /100.0190–0.0200
  1. P < 0.05 in bold
  2. COX-1 rs1330344, rs3842788, COX-2 rs689466 signed as SNP1–3
  3. CVC(cross-validation consistency)