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Table 5 Additive effect analysis between three SNPs

From: Interaction between COX-1 and COX-2 increases susceptibility to ischemic stroke in a Chinese population

Risk loci

control(%)

IS

LAA

n(%)

OR(95% CI)

P value

n(%)

OR(95% CI)

P value

0

22(2.4)

32(3.0)

Reference

 

13(3.2)

Reference

 

1

230(25.5)

294(27.3)

0.856(0.341–2.151)

0.741

105(25.9)

0.646(0.215–1.942)

0.437

2

586(64.9)

694(64.4)

0.752(0.323–1.752)

0. 509

270(66.7)

0.587 (0.216–1.595)

0.296

3

65(7.2)

58(5.4)

0.400(0.144–1.111)

0.079

17(4.2)

0.231(0.056–0.951)

0.052

Risk loci

control(%)

CES

SVO

n(%)

OR(95% CI)

P value

n(%)

OR(95% CI)

P value

0

22(2.4)

4(2.9)

Reference

 

15(2.8)

Reference

 

1

230(25.5)

33(24.3)

0.881(0.231–3.645)

0.861

156(29.1)

1.178(0.388–3.576)

0.773

2

586(64.9)

88(64.7)

0.677 (0.183–2.502)

0.558

336(62.6)

0.747 (0.272–2.050)

0.572

3

65(7.2)

11(8.1)

0.220 (0.023–2.147)

0.193

30(5.6)

0.493 (0.148–1.644)

0.250

  1. Using multivariate analysis after adjusting for age, gender and traditional risk factors