Fig. 4
From: PPAR-γ promotes p38 MAP kinase-mediated endothelial cell permeability through activating Sirt3
PPAR-γ agonist promotes Sirt3 expression and activation. A, mRNA (a) and protein levels (b) of Sirt3 after PPAR-γ agonist treatment (in doses of 10, 20, and 50 uM and compared to non-treatment control) at 24 h of reperfusion of I/R injury HBMECs. c, Luciferase assays showed the activation of SIRT3 promoter region after PPAR-γ agonist treatment (in doses of 10, 20, and 50 uM and compared to non-treatment control) at 24 h of reperfusion of I/R injury HBMECs. ***, p < 0.001 comparing individual column to the column on the left