An investigation of oxidant/antioxidant balance in patients with migraine: a case-control study

BMC Neurology

Table 2 Serum inflammatory, oxidative and antioxidant biomarkers in migraine patients compared to healthy controls

Variable	Controls (n = 19)		Episodic Migraineurs (n = 44)		Chronic Migraineurs (n = 27)		P value
Variable	Mean	SD	Mean	SD	Mean	SD	P value
CAT (pg/ml)	8075.95^a	462.79	5452.14 ^a	891.98	3354.00 ^a	414.57	0.000
SOD (pmol/ml)	5117.37 ^a	183.90	5086.23 ^b	514.48	4210.63 ^a,b	308.28	0.000
GPx-1 (pg/ml)	4168.58 ^a	322.74	4284.23 ^b	178.71	4441.04 ^a,b	234.15	0.001
TEAC (pmol/ml)	136,203.68 ^a	7023.84	137,281.59 ^b	14,685.31	103,637.41 ^a,b	7197.49	0.000
NO (pg/ml)	5101.68 ^a	489.09	6461.23 ^a	744.32	7329.81 ^a	775.34	0.000
MDA (pg/ml)	3125.53 ^a	251.73	3844.93 ^a	349.75	5005.19 ^a	138.38	0.000

CAT, Catalase. SOD, Superoxide dismutase. GPx-1, Glutathione peroxidase-1. TEAC, Trolox equivalent antioxidant capacity. NO, nitric oxide. MDA, malondialdehyde. SD, Standard deviation

ISSN: 1471-2377