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Table 2 Standardised monthly total, associated and epilepsy-related healthcare cost over follow-up period in the matched population

From: Comparing healthcare cost associated with the use of enzyme-inducing and non-enzyme active antiepileptic drugs in elderly patients with epilepsy in the UK: a long-term retrospective, matched cohort study

Standardised monthly costs (2014 £)

 

EIAED

(n = 210)

nEAAED

(n = 210)

p-value

Total all direct healthcare costs

Median (range)

403 (50, 10,856)

317 (49, 5630)

 

Mean (SD)

749 (1091)

572 (710)

0.0150a

A&E visits

Median (range)

1 (0, 268)

0 (0, 316)

 

Mean (SD)

9 (24)

8 (28)

0.6764

AED medications

Median (range)

16 (2, 251)

8 (2, 420)

 

Mean (SD)

32 (38)

17 (36)

< 0.0001

GP practice consultations

Median (range)

159 (12, 1222)

146 (37, 1264)

 

Mean (SD)

199 (144)

195 (162)

0.7953

Inpatient hospitalisations

Median (range)

92 (0, 10,032)

25 (0, 4852)

 

Mean (SD)

422 (1007)

275 (595)

0.0694

Non-AED medications

Median (range)

24 (0, 797)

20 (0, 551)

 

Mean (SD)

46 (74)

43 (62)

0.6954

Outpatients, non-A&E referrals

Median (range)

4 (0, 489)

3 (0, 217)

 

Mean (SD)

18 (48)

11 (23)

0.0448

Test procedures

Median (range)

11 (0, 249)

12 (0, 518)

 

Mean (SD)

23 (36)

22 (45)

0.8992

Total epilepsy-related direct healthcare costs

Median (range)

52 (2, 4124)

23 (2, 1673)

 

Mean (SD)

196 (473)

100 (196)

0.0068

  1. ap-value based on a Mann Whitney U-test comparing distributions. All other p-values are based on t-test on differences in the mean costs between the cohorts. A&E Accident & Emergency, AED Antiepileptic drug, EIAED Enzyme-inducing AED, GP General practitioner, nEAAED Non-enzyme active AED, SD Standard deviation