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Table 1 Baseline clinical characteristics, vascular risk factors, stroke subtype, biochemical/cellular parameters and neuroimaging findings in patients with good or poor outcome at 3 months

From: Regulatory T cells participate in the recovery of ischemic stroke patients

VariableGood outcome
n = 87
Poor outcome
n = 117
P value
Age (years)57.4 ± 8.476.3 ± 7.3< 0.0001
Female gender, n (%)36(42.7)67(57.3)0.548
Previous hypertension, n (%)32(36.9)74(63.2)0.030
Previous diabetes, n (%)31(36.2)75(64.1)0.197
Previous dyslipidemia, n (%)28(32.5)79(67.5)0.016
Previous atrial fibrillation, n (%)40(46.7)63(53.8)< 0.0001
Previous ischemic cardiopathy, n (%)65(75.0)29(24.7)0.059
Previous peripheric arteriopathy, n (%)0(0)100 (100)0.220
Alcohol consumption, n (%)39(45.5)64(54.7)0.475
Smoking, n (%)47(54.5)53(45.3)0.052
Previous statin consumption, n (%)33(37.9)73(62.4)0.184
Leukocyte at admission (× 103/mmc)8.1 ± 1.78.7 ± 3.8< 0.0001
Glucose at admission (mg/dL)132.5 ± 39.3155.8 ± 89.2< 0.0001
Fibrinogen at admission (mg/dL)380.0 ± 64.9400.4 ± 101.8< 0.0001
CRP(C reactive protein) (mg/L)1.5 ± 1.73.2 ± 4.8< 0.0001
Recanalization therapy, n (%)55.644.40.433
Basal NIHSS4 [2, 7]13 [7, 18]< 0.0001
TOAST  0.003
 - Cardioembolic, n (%)27 (31.0)66 (56.4) 
 - Aterothrombotic, n (%)13 (14.9)13 (11.1) 
 - Lacunar, n (%)3 (3.4)4 (3.4) 
 - Undetermined, n (%)44 (56.4)34 (43.5) 
% Treg / total lymphocytes at admission0.0224 ± 0.01770.0197 ± 0.01120.962
% Treg / total lymphocytes, 48 h0.0715 ± 0.01330.0231 ± 0.0173< 0.0001
% Treg / total lymphocytes, 72 h0.0709 ± 0.00640.0273 ± 0.0183< 0.0001
% Treg / total lymphocytes, 7 days0.0515 ± 0.01890.0209 ± 0.01720.001