Table 1 Baseline clinical characteristics, vascular risk factors, stroke subtype, biochemical/cellular parameters and neuroimaging findings in patients with good or poor outcome at 3 months
From: Regulatory T cells participate in the recovery of ischemic stroke patients
Variable | Good outcome n = 87 | Poor outcome n = 117 | P value |
|---|---|---|---|
Age (years) | 57.4 ± 8.4 | 76.3 ± 7.3 | < 0.0001 |
Female gender, n (%) | 36(42.7) | 67(57.3) | 0.548 |
Previous hypertension, n (%) | 32(36.9) | 74(63.2) | 0.030 |
Previous diabetes, n (%) | 31(36.2) | 75(64.1) | 0.197 |
Previous dyslipidemia, n (%) | 28(32.5) | 79(67.5) | 0.016 |
Previous atrial fibrillation, n (%) | 40(46.7) | 63(53.8) | < 0.0001 |
Previous ischemic cardiopathy, n (%) | 65(75.0) | 29(24.7) | 0.059 |
Previous peripheric arteriopathy, n (%) | 0(0) | 100 (100) | 0.220 |
Alcohol consumption, n (%) | 39(45.5) | 64(54.7) | 0.475 |
Smoking, n (%) | 47(54.5) | 53(45.3) | 0.052 |
Previous statin consumption, n (%) | 33(37.9) | 73(62.4) | 0.184 |
Leukocyte at admission (× 103/mmc) | 8.1 ± 1.7 | 8.7 ± 3.8 | < 0.0001 |
Glucose at admission (mg/dL) | 132.5 ± 39.3 | 155.8 ± 89.2 | < 0.0001 |
Fibrinogen at admission (mg/dL) | 380.0 ± 64.9 | 400.4 ± 101.8 | < 0.0001 |
CRP(C reactive protein) (mg/L) | 1.5 ± 1.7 | 3.2 ± 4.8 | < 0.0001 |
Recanalization therapy, n (%) | 55.6 | 44.4 | 0.433 |
Basal NIHSS | 4 [2, 7] | 13 [7, 18] | < 0.0001 |
TOAST | 0.003 | ||
- Cardioembolic, n (%) | 27 (31.0) | 66 (56.4) | |
- Aterothrombotic, n (%) | 13 (14.9) | 13 (11.1) | |
- Lacunar, n (%) | 3 (3.4) | 4 (3.4) | |
- Undetermined, n (%) | 44 (56.4) | 34 (43.5) | |
% Treg / total lymphocytes at admission | 0.0224 ± 0.0177 | 0.0197 ± 0.0112 | 0.962 |
% Treg / total lymphocytes, 48 h | 0.0715 ± 0.0133 | 0.0231 ± 0.0173 | < 0.0001 |
% Treg / total lymphocytes, 72 h | 0.0709 ± 0.0064 | 0.0273 ± 0.0183 | < 0.0001 |
% Treg / total lymphocytes, 7 days | 0.0515 ± 0.0189 | 0.0209 ± 0.0172 | 0.001 |