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Table 3 Homocysteine levels before and after treatment according to MTHFR C677T genotype

From: A prospective cohort study of MTHFR C677T gene polymorphism and its influence on the therapeutic effect of homocysteine in stroke patients with hyperhomocysteinemia

  CC (n = 10) CT (n = 55) TT (n = 97) P value*
HCY before treatment, μmol/L 20.26 ± 6.60 18.90 ± 6.37 21.75 ± 8.19 0.049
HCY after treatment, μmol/L 14.02 ± 3.53 12.98 ± 5.01 ab 19.45 ± 11.32 ab 0.002
P value** 0.535 0.328 0.211  
  1. * Analysis of variance was used for comparison among genotypes
  2. ** Paired sample t-test was used for comparison between baseline and 1 month after treatment
  3. ab Different letters indicate statistical significance. Least significant difference (LSD) test was used for pairwise comparison. CCvsCT p = 0.816; CC vs TT p = 0.215; CT vs TT p = 0.001