Table 2 Data summary of Clinical Characteristics of of reported FXTAS cases
Total(n = 64) | Male (n = 44) | Female (n = 20) | P-valueb | |
|---|---|---|---|---|
Onset age (years old) | 60.5 (12.5)a | 59.0 (10.5) | 61.5 (14) | 0.376 |
Duration before diagnosis (years) | 5 .5(5.4)a | 4.8 (5.6) | 5.8 (5.2) | 0.026 |
Positive family history(%) | 44/59(74.6%) | 30/40(75.0) | 14/19(73.7%) | 0.905 |
Tremor(%) | 52/61(85.2%) | 33/41(80.5%) | 19/20(95.0%) | 0.135 |
Intention tremor(%) | 26/61(42.6%) | 15/41(36.6%) | 11/20(55.5%) | 0.171 |
Kinetic tremor(%) | 22/61(36.1%) | 17/41(41.5%) | 5/20(25.0%) | 0.209 |
Rest tremor(%) | 20/61(32.8%) | 13/41(31.7%) | 7/20(35.0%) | 0.802 |
Isolated rest tremor | 6/61(9.8%) | 2/41(4.9%) | 4/20(20.0%) | 0.063 |
Posture tremor(%) | 18/61(29.5%) | 12/41(29.3%) | 6/20(33.3%) | 0.952 |
Orthostatic tremor | 2/61(3.3%) | 1/41(2.4%) | 1/20(5.0%) | 0.603 |
voice tremor | 2/61(3.3%) | 1/41(2.4%) | 1/20(5.0%) | 0.603 |
Head tremor | 6/61(9.8%) | 3/41(7.3%) | 3/20(15%) | 0.346 |
More than two types of tremor(%) | 23/61(37.7%) | 17/41(41.5%) | 6/20(30.0%) | 0.386 |
Ataxia (%) | 52/64(81.3%) | 35/44(79.6%) | 17/20(85.0%) | 0.604 |
Parkinsonism(%) | 28/64(43.8%) | 19/44(43.2%) | 9/20(45.0%) | 0.623 |
Cognitive impairement(%) | 46/64(71.9%) | 34/44(77.3%) | 12/20(60.0%) | 0.154 |