Skip to main content

Table 2 Hot cross bun (HCB) sign on MRI in MSA and SCA3

From: Vertical pons hyperintensity and hot cross bun sign in cerebellar-type multiple system atrophy and spinocerebellar ataxia type 3

 Grade 1 or 2 HCB sign
(vertical or cruciform hyper-intensity)
Grade 2 HCB sign
(cruciform hyper-intensity)
All
 MSA (n = 80)51/80 (63.8%)39/80 (48.8%)
 MSA-C (n = 41)38/41 (92.7%)30/41 (73.2%)
 MSA-P (n = 39)13/39 (33.3%)9/39 (23.1%)
 SCA3 (n = 24)21/26 (80.8%)8/26 (30.8%)
 Controls (n = 22)0/22 (0%)0/22 (0%)
Within two years after onset
 MSA (n = 43)25/43 (58.1%)14/43 (32.6%)
 MSA-C (n = 24)22/24 (91.7%)13/24 (54.2%)
 MSA-P (n = 19)3/19 (15.8%)1/19 (5.3%)
 SCA3 (n = 4)2/4 (50.0%)0/4 (0%)
Within three years after onset
 MSA (n = 60)37/60 (61.7%)26/60 (43.3%)
 MSA-C (n = 36)33/36 (91.7%)24/36 (66.7%)
 MSA-P (n = 24)4/24 (16.7%)2/24 (8.3%)
 SCA3 (n = 8)4/8 (50.0%)0/8 (0%)