Table 2 Hot cross bun (HCB) sign on MRI in MSA and SCA3
Grade 1 or 2 HCB sign (vertical or cruciform hyper-intensity) | Grade 2 HCB sign (cruciform hyper-intensity) | |
|---|---|---|
All | ||
MSA (n = 80) | 51/80 (63.8%) | 39/80 (48.8%) |
MSA-C (n = 41) | 38/41 (92.7%) | 30/41 (73.2%) |
MSA-P (n = 39) | 13/39 (33.3%) | 9/39 (23.1%) |
SCA3 (n = 24) | 21/26 (80.8%) | 8/26 (30.8%) |
Controls (n = 22) | 0/22 (0%) | 0/22 (0%) |
Within two years after onset | ||
MSA (n = 43) | 25/43 (58.1%) | 14/43 (32.6%) |
MSA-C (n = 24) | 22/24 (91.7%) | 13/24 (54.2%) |
MSA-P (n = 19) | 3/19 (15.8%) | 1/19 (5.3%) |
SCA3 (n = 4) | 2/4 (50.0%) | 0/4 (0%) |
Within three years after onset | ||
MSA (n = 60) | 37/60 (61.7%) | 26/60 (43.3%) |
MSA-C (n = 36) | 33/36 (91.7%) | 24/36 (66.7%) |
MSA-P (n = 24) | 4/24 (16.7%) | 2/24 (8.3%) |
SCA3 (n = 8) | 4/8 (50.0%) | 0/8 (0%) |