Table 1 DSM-V Diagnostic Criteria for NMS [4]
A. Development of severe muscle rigidity and elevated temperature associated with the use of neuroleptic medication | |
B. Two (or more) of the following | |
1) Diaphoresis | |
2) Dysphagia | |
3) Tremor | |
4) Incontinence | |
6) Mutism | |
7) Tachycardia | |
8) Elevated or labile blood pressure | |
9) Leukocytosis | |
10) Laboratory evidence of muscle injury (eg, elevated creatine phosphokinase) | |
C. The symptoms in criteria A and B are not due to another substance or a neurological or other general medical condition | |
D. The symptoms in criteria A and B are not better accounted for by a mental disorder. |