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Table 3 Hazard Ratios and 95% Confidence Intervals for Ischemic Stroke Subtypes by Low-grade Albuminuria Among HUNT 2 Participants, (n = 7261)

From: Low grade albuminuria as a risk factor for subtypes of stroke - the HUNT Study in Norway

  Model 1Model 2
ACR, mg/mmolCases/Person time in yearsHR95% CIp for trendHR95% CIp for trend
Lacunar stroke
  < 196/557331(ref) 1(ref) 
 1 - < 238/165481.19(0.82–1.74) 1.09(0.75–1.6) 
 2 - < 311/37861.45(0.77–2.71) 1.25(0.66–2.35) 
  ≥ 328/61302.25(1.48–3.45)< 0.0011.75(1.12–2.72)0.019
Cardio-embolic stroke
  < 156/557331(ref) 1(ref) 
 1 - < 221/165480.98(0.59–1.62) 0.96(0.58–1.6) 
 2 - < 37/37861.36(0.62–2.98) 1.23(0.56–2.73) 
  ≥ 312/61301.43(0.76–2.67)0.2421.22(0.64–2.3)0.518
Large artery atherosclerotic stroke
  < 145/557331(ref) 1(ref) 
 1 - < 216/165481.03(0.58–1.83) 0.98(0.55–1.76) 
 2 - < 37/37861.87(0.84–4.16) 1.49(0.66–3.35) 
  ≥ 312/61302(1.05–3.79)0.0221.51(0.78–2.94)0.186
Stroke of other determined etiology
  < 16/557331(ref) 1(ref) 
 1 - < 22/165480.9(0.22–5.52) 1(0.19–5.13) 
 2 - < 30/3786      
  ≥ 32/61302.4(0.58–14.64)0.3532.09(0.37–11.72)0.619
Stroke of undetermined etiology
  < 1183/557331(ref) 1(ref) 
 1 - < 285/165481.16(0.9–1.51) 1.1(0.85–1.43) 
 2 - < 324/37861.38(0.9–2.12) 1.24(0.8–1.9) 
  ≥ 352/61301.83(1.34–2.49)< 0.0011.53(1.11–2.11)0.009
  1. ACR Urine albumin-creatinine ratio; CI Confidence interval; HR Hazard ratio
  2. Model 1 is age adjusted
  3. Model 2 is additionally adjusted for sex, smoking status, educational status, BMI, EGFR, DM, systolic blood pressure, non-HDL Cholesterol, Triglycerides