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Fig. 3 | BMC Neurology

Fig. 3

From: Intracranial-to-central venous pressure gap predicts the responsiveness of intracranial pressure to PEEP in patients with traumatic brain injury: a prospective cohort study

Fig. 3

Predictive values of PICGap, baseline ICP, and baseline CVP for ICP responsiveness to PEEP. Areas under the ROC curves (AUCs) were assessed for various parameters potentially predicting ICP responsiveness to PEEP adjustment. PICGap had the strongest ability to predict ICP responsiveness to PEEP increase (AUC = 0.957, 95%CI 0.918–0.996; p < 0.001) among the three parameters. Meanwhile, baseline ICP had overtly weaker predictive ability than PICGap (AUC = 0.782 for baseline ICP, 95%CI 0.693–0.781; p < 0.001), and baseline CVP had the weakest ability to predict the responsiveness (AUC = 0.660 for CVP, 95%CI 0.560–0.760; p = 0.004). Abbreviations: PICGap, gap between baseline ICP and baseline CVP; ICP, intracranial pressure; AUC, area under receiver operating characteristic curve; ROC, receiver operating characteristic

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