Table 1 Demographics for the PD and CTL groups
From: Extrastriatal 123I-FP-CIT SPECT impairment in Parkinson’s disease – the PPMI cohort
PD (n = 154) | CTL (n = 62) | p-value | |
|---|---|---|---|
Age (years) | 61.6 ± 8.9 (40–82) | 61.5 ± 10 (40–81) | 0.87 § |
Male distribution | 61.7% (98/154) | 61.5% (41/62) | 0.73 # |
Right-handedness | 90.3% (139/154) | 82.3% (51/62) | 0.19 # |
Disease duration (months) | 25.5 ± 17.8 (2–77) | NA | – |
MDS-UPDRS III at baseline | 22.3 ± 9.7 (5–46) | 0.5 ± 1.2 (0–8) | < 0.0001 § |
MDS-UPDRS III axial subscore | 4.0 ± 2.6 (0–12) | 0.1 ± 0.3 (0–2) | < 0.0001 § |
MDS-UPDRS III right-sided items subscore | 7.9 ± 4.8 (0–20) | 0.2 ± 0.5 (0–3) | < 0.0001 § |
MDS-UPDRS III left-sided items subscore | 7.7 ± 6.1 (0–23) | 0.3 ± 0.6 (0–3) | < 0.0001 § |
Hoehn-Yahr scale | 1.5 ± 0.5 (1–2) | 0 (0–0) | < 0.001 # |
MOCA | 27.4 ± 2.2 (20–30) | 28.2 ± 1.2 (26–30) | 0.19 § |
GDS | 5.3 ± 1.4 (1–11) | 5.1 ± 1.2 (3–10) | 0.39 § |
SCOPA-AUT | 10.5 ± 6.0 (0–40) | 7.5 ± 4.5 (0–19) | 0.0002 § |
SCOPA-AUT Gastrointestinal subscore | 2.3 ± 1.9 (0–11) | 0.8 ± 1.0 (0–4) | < 0.0001 § |
SCOPA-AUT Urological subscore | 3.9 ± 2.5 (0–14) | 3.2 ± 2.3 (0–12) | 0.03 § |
Epworth Sleepiness Scale | 6.2 ± 4.0 (0–19) | 5.9 ± 3.3 (0–15) | 0.68 § |
REM-sleep behavior disorder screening questionnaire | 4.3 ± 2.6 (1–12) | 2.9 ± 2.2 (0–10) | < 0.001 § |