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Table 1 Demographic and clinical characteristics of ischemic stroke patients with or without a TIA < 24 h. Results for continuous variables are presented as Mean ± SD, while discrete data are presented as percentage frequency. Pearson’s Chi-Square or Man Whitney U test as appropriate is used to compare differences between demographic and clinical characteristics in groups with or without a TIA < 24 h

From: Ischemic stroke with a preceding Trans ischemic attack (TIA) less than 24 hours and thrombolytic therapy

Demographic and clinical factors Acute Ischemic Stroke with TIA < 24 h Acute Ischemic Stroke without TIA < 24 h  
Number of patients 846 5469 P-value
Age Group: No. (%)
 < 50 97 (11.5) 658 (12.0) 0.299
 50–59 131 (15.5) 996 (18.2)  
 60–69 206 (24.3) 1299 (23.8)  
 70–79 195 (23.0) 1231 (22.5)  
 > =80 217 (25.7) 1285 (23.5)  
 Mean ± SD 68.08 ± 14.47 67.25 ± 14.73 0.126
Race: No (%)
 White 695 (82.2) 4288 (78.4) 0.042*a
 Black 130 (15.4) 1002 (18.3)  
 Other 21 (2.5) 179 (3.3)  
Gender: No. (%)
 Female 451 (53.3) 2807 (51.3) 0.283
 Male 395 (46.7) 2662 (48.7)  
Medical History: No. (%)
 Atrial Fib 118 (13.9) 924 (16.9) 0.032*a
 Coronary Artery Disease 283 (33.5) 1661 (30.4) 0.71
 Carotid Artery Stenosis 67 (7.9) 334 (6.1) 0.44*a
 Depression 125 (14.8) 721 (13.2) 0.206
 Diabetes 320 (37.8) 1935 (35.4) 0.167
 Drugs or Alcohol 31 (3.7) 337 (6.2) 0.004*a
 Dyslipidemia 492 (58.2) 2755 (50.4) < 0.001*a
 Stroke Family History 87 (10.3) 494 (9.0) 0.241
 Heart Failure 85 (10.0) 590 (10.8) 0.516
 Hormonal Replacement Therapy 11 (1.3) 79 (1.4) 0.742
 Hypertension 675 (79.8) 4306 (5469) 0.485
 Migraine 27 (3.2) 134 (2.5) 0.203
 Obesity 356 (42.1) 2311 (42.3) 0.923
 Previous Stroke 274 (32.4) 1424 (26.0) < 0.001*a
 Previous TIA 140 (16.5) 477 (8.7) < 0.001*a
 Prosthetic Heart Valve 11 (1.3) 62 (1.1) 0.673
 Peripheral Vascular Disease 84 (9.9) 400 (7.3) 0.008*a
 Chronic Renal Disease 66 (7.8) 447 (8.2) 0.713
 Sickle Cell 1 (0.1) 4 (0.1) 0.665
 Sleep Apnea 34 (4.0) 170 (3.1) 0.163
 Smoker 174 (20.6) 1486 (27.2) < 0.001*a
Medication History: No (%)
 HTN medication 625 (73.9) 3794 (69.4) 0.008*a
 Cholesterol Reducer 456 (53.9) 2428 (44.4) < 0.001*a
 Diabetes medication 269 (31.8) 1495 (27.3) 0.007*a
 Antidepressant 131 (15.5) 711 (13.0) 0.048*a
Initial NIHSS Score: No (%)
 0–9 677 (90.6) 3289 (71.7) < 0.001*
 10–14 53 (7.1) 507 (11.1)  
 15–20 12 (1.6) 501 (10.9)  
 21–25 5 (0.7) 290 (6.3)  
 Mean ± SD 3.46 ± 4.1 8.28 ± 8.24 < 0.001*b
Lab values: Mean ± SD
 Total cholesterol (mg/dl) 167.88 ± 44.01 171.84 ± 51.82 0.026*b
 Triglycerides (mg/dl) 146.38 ± 93.94 139.64 ± 105.16 0.1
 HDL (mg/dl) 42.81 ± 14.28 41.78 ± 13.84 0.062
 LDL (mg/dl) 98.22 ± 36.56 104.62 ± 41.29 < 0.001*b
 Lipids (mg/dl) 7.38 ± 26.21 6.53 ± 2.56 0.389
 Blood Glucose (mg/dl) 138.59 ± 76.92 147.3 ± 81.05 0.004*b
 Serum Creatinine (mg/dl) 1.44 ± 3.45 1.29 ± 1.17 0.288
 INR 1.19 ± 0.5 1.14 ± 0.5 0.036*b
Vital Signs: Mean ± SD
 Heart Rate 78.02 ± 14.86 82 ± 18.53 < 0.001*b
 Blood Pressure Systolic (mmHg) 148.61 ± 27.88 151.82 ± 29.31 0.003*b
 Blood Pressure Diastolic (mmHg) 79.37 ± 17.53 82.44 ± 19.12 < 0.001*b
  1. Notes:
  2. aPearson’s Chi-Squared test
  3. bStudent’s T test
  4. * P-value < 0.05