Table 1 Demographic and clinical characteristics of ischemic stroke patients with or without a TIA < 24 h. Results for continuous variables are presented as Mean ± SD, while discrete data are presented as percentage frequency. Pearson’s Chi-Square or Man Whitney U test as appropriate is used to compare differences between demographic and clinical characteristics in groups with or without a TIA < 24 h
Demographic and clinical factors | Acute Ischemic Stroke with TIA < 24 h | Acute Ischemic Stroke without TIA < 24 h |  |
|---|---|---|---|
Number of patients | 846 | 5469 | P-value |
Age Group: No. (%) | |||
 < 50 | 97 (11.5) | 658 (12.0) | 0.299 |
 50–59 | 131 (15.5) | 996 (18.2) |  |
 60–69 | 206 (24.3) | 1299 (23.8) |  |
 70–79 | 195 (23.0) | 1231 (22.5) |  |
 > =80 | 217 (25.7) | 1285 (23.5) |  |
 Mean ± SD | 68.08 ± 14.47 | 67.25 ± 14.73 | 0.126 |
Race: No (%) | |||
 White | 695 (82.2) | 4288 (78.4) | 0.042*a |
 Black | 130 (15.4) | 1002 (18.3) |  |
 Other | 21 (2.5) | 179 (3.3) |  |
Gender: No. (%) | |||
 Female | 451 (53.3) | 2807 (51.3) | 0.283 |
 Male | 395 (46.7) | 2662 (48.7) |  |
Medical History: No. (%) | |||
 Atrial Fib | 118 (13.9) | 924 (16.9) | 0.032*a |
 Coronary Artery Disease | 283 (33.5) | 1661 (30.4) | 0.71 |
 Carotid Artery Stenosis | 67 (7.9) | 334 (6.1) | 0.44*a |
 Depression | 125 (14.8) | 721 (13.2) | 0.206 |
 Diabetes | 320 (37.8) | 1935 (35.4) | 0.167 |
 Drugs or Alcohol | 31 (3.7) | 337 (6.2) | 0.004*a |
 Dyslipidemia | 492 (58.2) | 2755 (50.4) | < 0.001*a |
 Stroke Family History | 87 (10.3) | 494 (9.0) | 0.241 |
 Heart Failure | 85 (10.0) | 590 (10.8) | 0.516 |
 Hormonal Replacement Therapy | 11 (1.3) | 79 (1.4) | 0.742 |
 Hypertension | 675 (79.8) | 4306 (5469) | 0.485 |
 Migraine | 27 (3.2) | 134 (2.5) | 0.203 |
 Obesity | 356 (42.1) | 2311 (42.3) | 0.923 |
 Previous Stroke | 274 (32.4) | 1424 (26.0) | < 0.001*a |
 Previous TIA | 140 (16.5) | 477 (8.7) | < 0.001*a |
 Prosthetic Heart Valve | 11 (1.3) | 62 (1.1) | 0.673 |
 Peripheral Vascular Disease | 84 (9.9) | 400 (7.3) | 0.008*a |
 Chronic Renal Disease | 66 (7.8) | 447 (8.2) | 0.713 |
 Sickle Cell | 1 (0.1) | 4 (0.1) | 0.665 |
 Sleep Apnea | 34 (4.0) | 170 (3.1) | 0.163 |
 Smoker | 174 (20.6) | 1486 (27.2) | < 0.001*a |
Medication History: No (%) | |||
 HTN medication | 625 (73.9) | 3794 (69.4) | 0.008*a |
 Cholesterol Reducer | 456 (53.9) | 2428 (44.4) | < 0.001*a |
 Diabetes medication | 269 (31.8) | 1495 (27.3) | 0.007*a |
 Antidepressant | 131 (15.5) | 711 (13.0) | 0.048*a |
Initial NIHSS Score: No (%) | |||
 0–9 | 677 (90.6) | 3289 (71.7) | < 0.001* |
 10–14 | 53 (7.1) | 507 (11.1) |  |
 15–20 | 12 (1.6) | 501 (10.9) |  |
 21–25 | 5 (0.7) | 290 (6.3) |  |
 Mean ± SD | 3.46 ± 4.1 | 8.28 ± 8.24 | < 0.001*b |
Lab values: Mean ± SD | |||
 Total cholesterol (mg/dl) | 167.88 ± 44.01 | 171.84 ± 51.82 | 0.026*b |
 Triglycerides (mg/dl) | 146.38 ± 93.94 | 139.64 ± 105.16 | 0.1 |
 HDL (mg/dl) | 42.81 ± 14.28 | 41.78 ± 13.84 | 0.062 |
 LDL (mg/dl) | 98.22 ± 36.56 | 104.62 ± 41.29 | < 0.001*b |
 Lipids (mg/dl) | 7.38 ± 26.21 | 6.53 ± 2.56 | 0.389 |
 Blood Glucose (mg/dl) | 138.59 ± 76.92 | 147.3 ± 81.05 | 0.004*b |
 Serum Creatinine (mg/dl) | 1.44 ± 3.45 | 1.29 ± 1.17 | 0.288 |
 INR | 1.19 ± 0.5 | 1.14 ± 0.5 | 0.036*b |
Vital Signs: Mean ± SD | |||
 Heart Rate | 78.02 ± 14.86 | 82 ± 18.53 | < 0.001*b |
 Blood Pressure Systolic (mmHg) | 148.61 ± 27.88 | 151.82 ± 29.31 | 0.003*b |
 Blood Pressure Diastolic (mmHg) | 79.37 ± 17.53 | 82.44 ± 19.12 | < 0.001*b |