Table 1 Baseline characteristics during the first 24 h in the NICU
TP – TP (N = 817) | TP – NTP (N = 666) | NTP – TP (N = 980) | NTP – NTP (N = 4, 987) | P value | |
|---|---|---|---|---|---|
Age, years (median, [IQR]) | 67 (56, 78) | 65 (52, 76) | 64 (51, 75) | 63 (50, 75) | < 0.001 |
Gender: male (n (%)) | 537 (66) | 401 (60) | 544 (56) | 2467 (49) | < 0.001 |
BMI (median, [IQR]) | 26.6 (23.2, 31.4) | 27.4 (23.4, 32) | 27.4 (23.6, 32.3) | 27.5 (23.5, 32.4) | 0.019 |
Ethnicity (n (%)) | 0.504 | ||||
Caucasian | 621 (76) | 498 (75) | 720 (73) | 3669 (74) | |
African American | 108 (13) | 98 (15) | 143 (15) | 731 (15) | |
Hispanic | 32 (4) | 21 (3) | 41 (4) | 192 (4) | |
Asian | 15 (2) | 12 (2) | 15 (2) | 74 (1) | |
Native American | 10 (1) | 2 (0) | 4 (0) | 38 (1) | |
Other/Unknown | 31 (4) | 35 (5) | 57 (6) | 283 (6) | |
Comorbidities (n (%)) | |||||
Hypertension | 401 (49) | 322 (48) | 484 (49) | 2422 (49) | 0.96 |
Diabetes mellitus | 190 (23) | 130 (20) | 222 (23) | 1131 (23) | 0.288 |
Respiratory disease | 87 (11) | 65 (10) | 74 (8) | 465 (9) | 0.139 |
Heart failure | 105 (13) | 76 (11) | 90 (9) | 342 (7) | < 0.001 |
Cirrhosis | 82 (10) | 18 (3) | 17 (2) | 31 (1) | < 0.001 |
Chronic renal insufficiency | 116 (14) | 66 (10) | 96 (10) | 295 (6) | < 0.001 |
Cancer | 208 (25) | 103 (15) | 145 (15) | 633 (13) | < 0.001 |
Disease category (n (%)) | < 0.001 | ||||
Postoperation | 162 (20) | 169 (25) | 234 (24) | 1128 (23) | |
Ischemic stroke | 97 (12) | 82 (12) | 121 (12) | 964 (19) | |
Traumatic brain injury | 75 (9) | 62 (9) | 94 (10) | 341 (7) | |
Intracranial hemorrhage | 65 (8) | 51 (8) | 97 (10) | 551 (11) | |
Hematoma subdural | 54 (7) | 32 (5) | 42 (4) | 234 (5) | |
Epilepsy | 42 (5) | 35 (5) | 41 (4) | 216 (4) | |
Multiple Trauma | 37 (5) | 38 (6) | 59 (6) | 137 (3) | |
Subarachnoid hemorrhage | 15 (2) | 12 (2) | 26 (3) | 185 (4) | |
Neoplasm | 19 (2) | 6 (1) | 26 (3) | 215 (4) | |
Others | 251 (31) | 179 (27) | 240 (24) | 1016 (20) | |
Vital signs, (median, [IQR]) | |||||
Maximum Temperature, °C | 37.2 (36.9, 37.7) | 37.3 (37, 37.9) | 37.4 (37, 37.9) | 37.2 (36.9, 37.6) | < 0.001 |
Minimum Temperature, °C | 36.4 (36.1, 36.6) | 36.5 (36.1, 36.7) | 36.4 (36.1, 36.7) | 36.5 (36.2, 36.7) | < 0.001 |
Maximum HR, beats/min | 98 (86, 113) | 103 (89, 119) | 104 (90, 120) | 99 (87, 112) | < 0.001 |
Minimum HR, beats/min | 66 (58, 77) | 67 (59, 79) | 68 (59, 79) | 65 (58, 75) | < 0.001 |
Maximum RR | 26 (23, 30) | 26 (23, 31) | 26 (23, 31) | 26 (23, 30) | 0.034 |
Minimum RR | 12 (10, 14) | 12 (10, 14) | 12 (10, 14) | 12 (10, 14) | 0.076 |
Maximum MBP, mmHg | 104 (95, 117) | 105 (95, 119) | 106 (96, 120) | 107 (97, 121) | < 0.001 |
Minimum MBP, mmHg | 64 (55, 73) | 64 (56, 73) | 64 (56, 72) | 67 (59, 76) | < 0.001 |
Laboratory test, (median, [IQR]) | |||||
Maximum hemoglobin, g/dl | 12.2 (10.5, 13.8) | 12.5 (11.1, 14) | 13 (11.3, 14.5) | 12.9 (11.4, 14.2) | < 0.001 |
Minimum hemoglobin, g/dl | 10.84 (8.5, 12.5) | 10.9 (9.1, 12.5) | 11.4 (9.5, 13.1) | 11.9 (10.3, 13.2) | < 0.001 |
Maximum WBC, × 109/L | 8.9 (6.3, 13.1) | 10.8 (7.9,14.3) | 12.9 (9.7, 16.8) | 11.89 (9, 15.4) | < 0.001 |
Minimum WBC, × 109/L | 6.6 (4.7, 9.3) | 8 (6, 10.1) | 9.5 (7.1, 12.7) | 9.4 (7.4, 12.2) | < 0.001 |
Disease severity, (median, [IQR]) | |||||
APACHE IV score | 53 (41, 71) | 52 (39, 68) | 55 (38, 72) | 44 (33, 59) | < 0.001 |
GCS | 14 (10, 15) | 14 (9, 15) | 13 (8, 15) | 14 (11, 15) | < 0.001 |