Table 1 Baseline characteristics of 94 patients for the efficacy analyses
Characteristics | NBP group(n = 48) | Placebo group(n = 46) | P values |
|---|---|---|---|
Age (years) | 56.6 ± 11.5 | 60.6 ± 10.3 | 0.085 |
Gender (male) | 39 (81.2%) | 32 (69.6%) | 0.188 |
Hypertention (yes) | 38 (79.2%) | 39 (84.8%) | 0.479 |
Diabetes mellitus (yes) | 19 (39.6%) | 22 (47.8%) | 0.420 |
Hyperlipemia (yes) | 37 (77.1%) | 38 (82.6%) | 0.505 |
Coronary disease (yes) | 8 (16.7%) | 12 (26.1%) | 0.265 |
Smoking (yes) | 29 (60.4%) | 24 (52.2%) | 0.420 |
Previous TIA/ ischemic stroke | |||
Previous TIA | 8 (16.7%) | 9 (19.6%) | 0.600 |
Previous ischemic stroke | 24 (50.0%) | 26 (56.5) | |
None | 16 (33.3%) | 11 (23.9%) | |
Methods for assessing stenosis | |||
MRA | 35 (72.9%) | 30 (65.2%) | 0.316 |
CTA | 1 (2.1%) | 0 (0%) | |
DSA | 12 (25.0%) | 16 (34.8%) | |
Unilateral or bilateral | |||
Right side | 20 (41.7%) | 22 (47.8%) | 0.526 |
Left side | 22 (45.8%) | 16 (34.8%) | |
Bilateral | 6 (12.5%) | 8 (17.4%) | |
Stenotic location | |||
Extracranial ICA | 10 (20.8%) | 8 (17.4%) | 0.118 |
Intracranial ICA | 23 (47.9%) | 31 (67.4%) | |
MCA(M1 segment) | 15 (31.2%) | 7 (15.2%) | |
Carotid stenotic degree | |||
Severe stenosis(70–99%) | 35 (72.9%) | 40 (87.0%) | 0.090 |
Occlusion | 13 (27.1%) | 6 (13.0%) | |
Integrity of CoW | |||
Integrity | 11 (22.9%) | 17 (37.0%) | 0.137 |
Un-integrity | 37 (77.1%) | 29 (63.0%) | |
Time of follow-up (months) | 3.7 ± 1.6 | 3.5 ± 0.9 | 0.516 |
Discontinuation of OMT (yes) | 5 (10.4%) | 3 (6.5%) | 0.759 |