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Table 3 Odds ratios of NBP vs. placebo for whole CBF outcomes in ipsilateral MCA territory of carotid artery system stenosis

From: DL-3-n-butylphthalide improves cerebral hypoperfusion in patients with large cerebral atherosclerotic stenosis: a single-center, randomized, double-blind, placebo-controlled study

Models

Adjusted factors

Wald-χ2

P values

OR(95%CI)

1

None

6.080

0.014

3.23 (1.02–8.19)

2

Demographics and atherosclerotic risk factors

5.687

0.017

3.38 (1.24–9.19)

3

Demographics, atherosclerotic risk factors, cerebral stenotic characteristics and integrity of CoW

5.247

0.022

3.31 (1.19–9.20)

4

Demographics, atherosclerotic risk factors, cerebral stenotic characteristics and integrity of CoW, OMT

5.110

0.024

3.26 (1.17–9.06)

  1. NBP Dl-3-butylphthalide, CBF cerebral blood flow, MCA middle cerebral artery, CoW circle of Willis. Demographics included age and sex; Atherosclerotic risk factors included hypertention, diabetes mellitus, hyperlipemia, coronary disease and smoking; Cerebral stenotic characteristics included bilateral stenosis and stenotic degree. OMT = optimized medical therapy
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BMC Neurology

ISSN: 1471-2377

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