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Table 3 Odds ratios of NBP vs. placebo for whole CBF outcomes in ipsilateral MCA territory of carotid artery system stenosis

From: DL-3-n-butylphthalide improves cerebral hypoperfusion in patients with large cerebral atherosclerotic stenosis: a single-center, randomized, double-blind, placebo-controlled study

ModelsAdjusted factorsWald-χ2P valuesOR(95%CI)
1None6.0800.0143.23 (1.02–8.19)
2Demographics and atherosclerotic risk factors5.6870.0173.38 (1.24–9.19)
3Demographics, atherosclerotic risk factors, cerebral stenotic characteristics and integrity of CoW5.2470.0223.31 (1.19–9.20)
4Demographics, atherosclerotic risk factors, cerebral stenotic characteristics and integrity of CoW, OMT5.1100.0243.26 (1.17–9.06)
  1. NBP Dl-3-butylphthalide, CBF cerebral blood flow, MCA middle cerebral artery, CoW circle of Willis. Demographics included age and sex; Atherosclerotic risk factors included hypertention, diabetes mellitus, hyperlipemia, coronary disease and smoking; Cerebral stenotic characteristics included bilateral stenosis and stenotic degree. OMT = optimized medical therapy