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Table 1 Baseline Characteristics of Patients in the Derivation Cohort (n = 250)

From: Early prediction of cerebral-cardiac syndrome after ischemic stroke: the PANSCAN scale

Characteristics

 

no CCS, n = 112

CCS, n = 138

P-value

Age, n (%)

< 65

76 (67.9)

50 (36.2)

< 0.001*

≥65

36 (32.1)

88 (63.8)

 

Sex, n (%)

Male

70 (62.5)

56 (40.6)

0.001*

Female

42 (37.5)

82 (59.4)

 

Stroke location, n (%)

Brain stem

18 (16.1)

30 (21.7)

0.155

Others

94 (83.9)

98 (71.0)

 

Temperature(°C), n (%)

<37.5

98 (87.5)

118 (85.5)

0.713

≥37.5

14 (12.5)

20 (14.5)

 

Mean Arterial Pressure (mmHg), n (%)

Normal(<105)

44 (39.3)

60 (43.5)

0.521

Elevated(≥105)

68 (60.7)

78 (56.5)

 

GCS Score, n (%)

Conscious(15)

108 (96.4)

120 (87.0)

0.027*

Mild(12 ~ 14)

2 (1.8)

12 (8.7)

 

Moderate(9 ~ 11)

0 (0.0)

4 (2.9)

 

Coma(≤8)

2 (1.8)

2 (1.4)

 

NIHSS Score, n (%)

0

54 (48.2)

20 (14.5)

< 0.001*

1 ~ 4

44 (39.3)

60 (43.5)

 

> 4

14 (12.5)

58 (42.0)

 

Hypertension, n (%)

No

32 (28.6)

58 (42.0)

0.34

Yes

80 (71.4)

80 (58.0)

 

Diabetes, n (%)

No

82 (74.5)

96 (70.6)

0.567

Yes

28 (25.5)

40 (29.4)

 

Stroke Times, n (%)

1 times

96 (85.7)

110 (79.7)

0.245

> 1 times

16 (14.3)

28 (20.3)

 

Smoking history, n (%)

No

104 (92.9)

122 (88.4)

0.284

Yes

8 (7.1)

16 (11.6)

 

Drinking history, n (%)

No

72 (64.3)

98 (71.0)

0.277

Yes

40 (35.7)

40 (29.0)

 

WBC(10^9/L), median (IQR)

 

6.30 (5.60, 8.18)

6.75 (5.43, 8.90)

0.497

Neutrophil(%), median (IQR)

 

61.3 (56.1, 66.1)

66.0 (59.6, 76.0)

< 0.01*

PT(s), median (IQR)

 

13.0 (12.3, 13.9)

13.6 (12.8, 15.1)

0.012*

APTT(s), median (IQR)

 

36.6 (34.4, 38.3)

37.2 (34.4, 42.0)

0.031*

Fibrinogen(g/L), median (IQR)

 

3.29 (2.80, 3.83)

2.96 (2.51, 3.80)

0.022*

D-Dimer(< 500 μg/l FEU), median (IQR)

 

390.0 (300.0, 630.0)

490.0 (300.0, 1130.0)

0.023*

GPT(U/L), median (IQR)

 

18.0 (13.0,29.0)

17.0 (13.0,27.0)

0.609

GOT(U/L), median (IQR)

 

22.0 (19.0,27..8)

23.0 (18.0,28.5)

0.813

Serum Potassium, median (mmol/l)(IQR)

 

3.72 (3.48,3.89)

3.79 (3.37,3.95)

0.997

Blood Glucose, median (mmol/l) (IQR)

 

5.22 (4.75,6.41)

5.21 (4.66,7.27)

0.760

BUN (mmol/l), median (IQR)

 

4.59 (3.67,5.61)

5.00 (4.15,6.14)

0.037*

Serum creatinine (mmol/l),median (IQR)

 

58.0 (49.3,70.8)

59.0 (47.8,71.5)

0.784

Triglycerides (mmol/l), median (IQR)

 

1.31 (0.98,1.69)

1.20 (0.87,1.57)

0.098

LDL (mmol/l), median (IQR)

 

2.28 (1.77,2.97)

2.10 (1.48,2.55)

0.010

IMT, n (%)

Normal

35 (34.7)

42 (34.1)

0.483

Thicken

66 (65.3)

81 (65.9)

 

Carotid Stenosis, n (%)

Normal

56 (55.4)

42 (33.6)

< 0.001*

Mild

36 (35.7)

47 (37.6)

 

Moderate to Severe

9 (8.9)

36 (28.8)

 

LVEF(%), n (%)

< 50

2 (2.2)

6 (5.0)

0.014*

50 ~ 55

0 (0.0)

3 (2.5)

 

55 ~ 60

14 (15.1)

27 (22.3)

 

≥60

77 (82.8)

85 (70.2)

 
  1. *indicated P < 0.05
  2. Abbreviations: GCS Glasgow coma scale, NIHSS National Institutes of Health Stroke Scale, WBC White blood cell, GPT Glutamic Pyruvic Transaminase, GOT Glutamic-Oxalacetic Transaminease, BUN Blood Urea Nitrogen, LDL Low Density Lipoprotein, IMT Intima-Media Thickness, LVEF Left Ventricular Ejection Fraction, IQR interquartile range, FEU Fibrinogen Equivalent Units