Table 1 Patient demographics, clinical and radiological findings
Patient Number | GCS | Neurological deficits | Steroids | Clinical signs of ICH | Tumor location | Histology | Concomitand disease | Maximal tumor diameter (cm) | Tumor structure | Tumor volume (cm3) | Edema volume (cm3) | Midline shift | Hemorrhage | Hydrocephalus | Non-invasive absolute ICP left / right |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 15 | apraxia, visual field restriction left side, vision impairement left side | no | none | Bilateral parafalcine occipital | Meningeoma Grade II | Hypertension Diabetes mellitus Typ II | 4.7 × 5.4 × 8.1 | solid with homogeneously contrast enhancement | 106.226 | 151.439 | 2.5 mm | none | none | 10.4 / 6 |
2 | 15 | absences, focal seizures | no | none | Left frontal | Diffuse Astrocytoma Grade II | none | 2.6 × 4.0 × 5.0 | T2 hyperdens / T1 hypodens lesion without contrast enhancement | 33.723 | 0.000 | none | none | none | 9.94 / 7.95 |
3 | 14 | focal and secondarily generalized seizures | yes | none | Left temporal | Glioblastoma multiforme | Hypertension Alcohol abuse | 4.0 × 2.7 × 3.9 | T2 hyperdens / T1 hypodens lesion without contrast enhancement | 24.985 | 0.000 | none | none | none | 7.14 / 10.43 |
4 | 15 | focal seizures | no | none | Multifocal (right thalamus, left parietal, right frontal right) | Astrocytoma Grade III - IV | Metabolic syndrome GIST Tumor of the stomach | 3.1 × 3.1 × 4.0 | multifocal central necrotic lesion with margin contrast enhancement | 30.217 | 89.075 | 3 mm | none | none | 10.09 / 9.15 |
5 | 15 | absences, memory disorders | yes | none | Left temporal | Meningeoma Grade I | none | 2.5 × 3.1 × 2.5 | solid with homogeneously contrast enhancement | 10.306 | 115.310 | 5.3 mm | none | none | 10.82 / - |
6 | 15 | gerstmann syndrome, aphasie | no | none | Left temporo-occipital | Metastasis | Renal cell carcinoma | 1.9 × 2.0 × 2.2 | central necrotic lesion with homogeneously contrast enhancement | 5.450 | 67.337 | none | yes | none | 7.0 / - |
7 | 15 | vertigo | yes | headache, nausea, vomitting | Right cerebellum | Metastasis | Hypertension Breast cancer | 3.7 × 4.2 × 2.7 | solid with moderate non homogeneously contrast enhancement | 23.783 | 10.304 | none | none | none | 10.5 / 12.71 |
8 | 14 | neglect, apraxia | no | none | Right parietal | Glioblastoma multiforme | Metabolic Syndrom Coronary heart disease Cerebrovascular and peripheral occlusive disease COPD | 3.7 × 6.2 × 5.5 | central necrotic lesion with margin contrast enhancement | 62.100 | 47.995 | 2 mm | none | none | 12.57 / 11.43 |
9 | 14 | neurocognitive deficits | no | none | Bilateral frontal parafalcine | Meningeoma Grade I | none | 5.7 × 4.6 × 5 | solid with homogeneously contrast enhancement | 56.933 | 0.000 | 9 mm | none | none | 5.5 / 9.9 |
10 | 14 | neurocognitive deficits | no | none | Left Temporal | Meningeoma Grade I | Metabolic Syndrom Breast Cancer Status following pulmonary embolism | 3.9 × 3.5 × 2.8 | solid with homogeneously contrast enhancement | 23.421 | 2.325 | none | none | none | 10.45 / 16.72 |
11 | 15 | none | yes | none | Right frontal | Meningeoma Grade I | Coronary heart disease Status following pulmonary embolism | 2.1 × 2.4 × 1.9 | solid with homogeneously contrast enhancement | 7.077 | 117.318 | none | none | none | 5.52 / 5.53 |
12 | 15 | vertigo, unsteadiness, diplopia | yes | headache | Vermis cerebelli | Metastasis | Breast Cancer | 4.2 × 3.7 × 3.8 | solid with moderate contrast enhancement | 25.550 | 36.790 | none | none | yes | 5.59 / 10.70 |
13 | 15 | hemiplegia right side | yes | none | Left frontal | Metastasis | Prostate Cancer Squamous skin cancer Metabolic syndrome Malignant melanoma | 2.2 × 3.8 × 3.1 | central necrotic lesion with margin contrast enhancement | 11.619 | 45.586 | none | none | none | 7.59 / 5.22 |
14 | 15 | vertigo | yes | headache | Left cerebellum | Meningeoma Grade I | TIA prior to admission | 3.5 × 4.2 × 3.9 | solid with homogeneously moderate contrast enhancement | 26.960 | 8.591 | none | none | yes | 11.0 / 6.0 |
15 | 15 | hemiparesis right side, unsteadiness | yes | none | Left parietal | Glioblastoma | Hypertension | 3.6 × 5.3 × 4.6 | central necrotic lesion with margin contrast enhancement | 50.717 | 85.340 | none | none | none | 8.0 / 8.1 |
16 | 14 | hemiparesis left side, focal seizures, neurocognitive maladjustment | no | none | Bilateral Corpus Callosum | Non - Hodgkin Lymphoma B-cell type | Delusional disorder | 5.2 × 3.5 × 2.3 | solid with inhomogeneously contrast enhancement | 31.731 | 196.777 | none | none | none | 8.34 / 8.16 |
17 | 14 | hemiparesis left side, neurocognitive deficits | yes | headache | Right Parieto-occipito-temporal | Metastasis | Schizophrenia Lung carcinoma | 7.6 × 6.0 × 5.7 | central necrotic lesion with margin contrast enhancement | 177.348 | 18.703 | 14 mm | yes | yes | - / 10.67 |
18 | 15 | gerstmann syndrome, neurocognitive deficits | no | none | Left parieto-occipital left with infiltration of Splenium Corpus callosum | Non - Hodgkin Lymphoma B-cell type | Coronary atherosclerosis | 5.8 × 5.2 × 3.6 | central necrotic lesion with thick margin contrast enhancement | 36.495 | 231.438 | 15 mm | none | yes | 9.08 / 11.00 |
19 | 15 | neurocognitive deficits, incoordination | yes | headache | Right frontal right side with infiltration of the thalamus | Astrocytoma Grade III | None | 6.1 × 8.0 × 8.8 | central necrotic and cystic wide spreading, diffuse lesion with only punctual contrast enhancement | 220.271 | 25.399 | 13 mm | none | yes | 6.0 / 7.5 |
20 | 15 | none | yes | headache | Right occipito-temporal | Metastasis | Pancoast tumor | 2.2 × 2.9 × 3.1 | solid with inhomogeneously contrast enhancement | 11.299 | 238.269 | 16 mm | none | none | 14.5 / - |