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Table 1 Patient demographics, clinical and radiological findings

From: Changing the paradigm of intracranial hypertension in brain tumor patients: a study based on non-invasive ICP measurements

Patient Number GCS Neurological deficits Steroids Clinical signs of ICH Tumor location Histology Concomitand disease Maximal tumor diameter (cm) Tumor structure Tumor volume (cm3) Edema volume (cm3) Midline shift Hemorrhage Hydrocephalus Non-invasive absolute ICP left / right
1 15 apraxia, visual field restriction left side, vision impairement left side no none Bilateral parafalcine occipital Meningeoma Grade II Hypertension
Diabetes mellitus
Typ II
4.7 × 5.4 × 8.1 solid with homogeneously contrast enhancement 106.226 151.439 2.5 mm none none 10.4 / 6
2 15 absences, focal seizures no none Left frontal Diffuse Astrocytoma Grade II none 2.6 × 4.0 × 5.0 T2 hyperdens / T1 hypodens lesion without contrast enhancement 33.723 0.000 none none none 9.94 / 7.95
3 14 focal and secondarily generalized seizures yes none Left temporal Glioblastoma multiforme Hypertension
Alcohol abuse
4.0 × 2.7 × 3.9 T2 hyperdens / T1 hypodens lesion without contrast enhancement 24.985 0.000 none none none 7.14 / 10.43
4 15 focal seizures no none Multifocal (right thalamus, left parietal, right frontal right) Astrocytoma Grade III - IV Metabolic syndrome
GIST Tumor of the stomach
3.1 × 3.1 × 4.0 multifocal central necrotic lesion with margin contrast enhancement 30.217 89.075 3 mm none none 10.09 / 9.15
5 15 absences, memory disorders yes none Left temporal Meningeoma Grade I none 2.5 × 3.1 × 2.5 solid with homogeneously contrast enhancement 10.306 115.310 5.3 mm none none 10.82 / -
6 15 gerstmann syndrome, aphasie no none Left temporo-occipital Metastasis Renal cell carcinoma 1.9 × 2.0 × 2.2 central necrotic lesion with homogeneously contrast enhancement 5.450 67.337 none yes none 7.0 / -
7 15 vertigo yes headache, nausea, vomitting Right cerebellum Metastasis Hypertension
Breast cancer
3.7 × 4.2 × 2.7 solid with moderate non homogeneously contrast enhancement 23.783 10.304 none none none 10.5 / 12.71
8 14 neglect, apraxia no none Right parietal Glioblastoma
multiforme
Metabolic Syndrom
Coronary heart disease
Cerebrovascular and peripheral occlusive disease
COPD
3.7 × 6.2 × 5.5 central necrotic lesion with margin contrast enhancement 62.100 47.995 2 mm none none 12.57 / 11.43
9 14 neurocognitive deficits no none Bilateral frontal parafalcine Meningeoma Grade I none 5.7 × 4.6 × 5 solid with homogeneously contrast enhancement 56.933 0.000 9 mm none none 5.5 / 9.9
10 14 neurocognitive deficits no none Left Temporal Meningeoma Grade I Metabolic Syndrom
Breast Cancer
Status following pulmonary embolism
3.9 × 3.5 × 2.8 solid with homogeneously contrast enhancement 23.421 2.325 none none none 10.45 / 16.72
11 15 none yes none Right frontal Meningeoma Grade I Coronary heart disease
Status following pulmonary embolism
2.1 × 2.4 × 1.9 solid with homogeneously contrast enhancement 7.077 117.318 none none none 5.52 / 5.53
12 15 vertigo, unsteadiness, diplopia yes headache Vermis cerebelli Metastasis Breast Cancer 4.2 × 3.7 × 3.8 solid with moderate contrast enhancement 25.550 36.790 none none yes 5.59 / 10.70
13 15 hemiplegia right side yes none Left frontal Metastasis Prostate Cancer Squamous skin cancer
Metabolic syndrome
Malignant melanoma
2.2 × 3.8 × 3.1 central necrotic lesion with margin contrast enhancement 11.619 45.586 none none none 7.59 / 5.22
14 15 vertigo yes headache Left cerebellum Meningeoma Grade I TIA prior to admission 3.5 × 4.2 × 3.9 solid with homogeneously moderate contrast enhancement 26.960 8.591 none none yes 11.0 / 6.0
15 15 hemiparesis right side, unsteadiness yes none Left parietal Glioblastoma Hypertension 3.6 × 5.3 × 4.6 central necrotic lesion with margin contrast enhancement 50.717 85.340 none none none 8.0 / 8.1
16 14 hemiparesis left side, focal seizures, neurocognitive maladjustment no none Bilateral Corpus Callosum Non - Hodgkin Lymphoma B-cell type Delusional disorder 5.2 × 3.5 × 2.3 solid with inhomogeneously contrast enhancement 31.731 196.777 none none none 8.34 / 8.16
17 14 hemiparesis left side, neurocognitive deficits yes headache Right Parieto-occipito-temporal Metastasis Schizophrenia Lung carcinoma 7.6 × 6.0 × 5.7 central necrotic lesion with margin contrast enhancement 177.348 18.703 14 mm yes yes - / 10.67
18 15 gerstmann syndrome, neurocognitive deficits no none Left parieto-occipital left with infiltration of Splenium Corpus callosum Non - Hodgkin Lymphoma B-cell type Coronary atherosclerosis 5.8 × 5.2 × 3.6 central necrotic lesion with thick margin contrast enhancement 36.495 231.438 15 mm none yes 9.08 / 11.00
19 15 neurocognitive deficits, incoordination yes headache Right frontal right side with infiltration of the thalamus Astrocytoma Grade III None 6.1 × 8.0 × 8.8 central necrotic and cystic wide spreading, diffuse lesion with only punctual contrast enhancement 220.271 25.399 13 mm none yes 6.0 / 7.5
20 15 none yes headache Right occipito-temporal Metastasis Pancoast tumor 2.2 × 2.9 × 3.1 solid with inhomogeneously contrast enhancement 11.299 238.269 16 mm none none 14.5 / -
  1. Abbr.: GCS Glasgow Coma Scale, ICH intracranial hypertension, ICP Intracranial Pressure