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Table 3 Canonical pathways modulated in the inferior horn of the lateral ventricles of AD patients, their aged-matched controls and nonagenarians. Identified canonical pathways generated from the list of significantly modulated proteins across three groups of interests using Ingenuity pathway analyses (IPA). FDR adjusted P value after Fischer’s test and Benjamin Hochberg correction following uploading of significantly regulated proteins into IPA (significant cut-off set at 0.01). Control vs nonagenarians (9 pathways identified), control vs AD (12 pathways identified), control vs nonagenarians (5 pathways identified). Blue represents upregulated pathways and Red represents downregulated pathways

From: Molecular abnormalities in autopsied brain tissue from the inferior horn of the lateral ventricles of nonagenarians and Alzheimer disease patients