Skip to main content

Table 3 Comparison of optic nerve sheath diameter related parameters, midline shift, and hemorrhagic patterns on postprocedure and D1 CT images according to early and late malignant progression

From: Optic nerve sheath diameter change in prediction of malignant cerebral edema in ischemic stroke: an observational study

CTpostprocedure    
  Early malignant progressors
(n = 12)
Nonprogressors
(n = 46)
P-value
CTbaseline to malignant progression, hr 10.8 ± 7.4   
Δ time (CTPostprocedure-CTbaseline), hr 3.9 ± 1.2 4.2 ± 3.2 0.716
ONSD (mm) 5.92 ± 0.56 5.81 ± 0.71 0.599
ONSD/ETD ratio, % 26.24 ± 1.99 25.45 ± 2.9 0.382
Δ ONSD/ETD ratio, % 3.70 ± 2.78 1.89 ± 3.37 0.093
MLS (mm) 6.08 ± 4.82 1.69 ± 2.21 0.009
Hemorrhagic pattern    < 0.001
No hemorrhage 0 (0.0%) 14 (30.4%)  
HI 1 0 (0.0%) 10 (21.7%)  
HI 2 1 (8.3%) 12 (26.1%)  
PH 1 4 (33.3%) 4 (8.7%)  
PH 2 7 (58.3%) 6 (13.0%)  
CTD1    
  Late malignant progressors
(n = 7)
Nonprogressors
(n = 39)
P-value
CTbaseline to malignant progression, hr 52.6 ± 51.5   
Δ time (CTD1-CTbaseline), hr 20.0 ± 11.3 27.4 ± 11.9 0.136
ONSD (mm) 6.10 ± 0.36 5.67 ± 0.74 0.138
ONSD/ETD ratio, % 26.93 ± 2.64 24.83 ± 2.94 0.085
Δ ONSD/ETD ratio, % 3.60 ± 2.67% 1.05 ± 2.69 0.025
MLS (mm) 6.55 ± 2.87 3.64 ± 3.68 0.054
Hemorrhagic pattern    0.819
No hemorrhage 3 (42.9%) 22 (56.4%)  
HI 1 1 (14.3%) 7 (17.9%)  
HI 2 1 (14.3%) 4 (10.3%)  
PH 1 2 (28.6%) 6 (15.4%)  
PH 2 0 (0.0%) 0 (0.0%)  
  1. Values are presented as mean ± SD, number (%), or median (interquartile range)
  2. CT Computed tomography angiography, ONSD Optic nerve sheath diameter, ETD Eyeball transverse diameter, MLS Midline shift, HI Hemorrhagic infarct, PH Parenchymal hematoma