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Table 3 Comparison of optic nerve sheath diameter related parameters, midline shift, and hemorrhagic patterns on postprocedure and D1 CT images according to early and late malignant progression

From: Optic nerve sheath diameter change in prediction of malignant cerebral edema in ischemic stroke: an observational study

CTpostprocedure

   
 

Early malignant progressors

(n = 12)

Nonprogressors

(n = 46)

P-value

CTbaseline to malignant progression, hr

10.8 ± 7.4

  

Δ time (CTPostprocedure-CTbaseline), hr

3.9 ± 1.2

4.2 ± 3.2

0.716

ONSD (mm)

5.92 ± 0.56

5.81 ± 0.71

0.599

ONSD/ETD ratio, %

26.24 ± 1.99

25.45 ± 2.9

0.382

Δ ONSD/ETD ratio, %

3.70 ± 2.78

1.89 ± 3.37

0.093

MLS (mm)

6.08 ± 4.82

1.69 ± 2.21

0.009

Hemorrhagic pattern

  

< 0.001

No hemorrhage

0 (0.0%)

14 (30.4%)

 

HI 1

0 (0.0%)

10 (21.7%)

 

HI 2

1 (8.3%)

12 (26.1%)

 

PH 1

4 (33.3%)

4 (8.7%)

 

PH 2

7 (58.3%)

6 (13.0%)

 

CTD1

   
 

Late malignant progressors

(n = 7)

Nonprogressors

(n = 39)

P-value

CTbaseline to malignant progression, hr

52.6 ± 51.5

  

Δ time (CTD1-CTbaseline), hr

20.0 ± 11.3

27.4 ± 11.9

0.136

ONSD (mm)

6.10 ± 0.36

5.67 ± 0.74

0.138

ONSD/ETD ratio, %

26.93 ± 2.64

24.83 ± 2.94

0.085

Δ ONSD/ETD ratio, %

3.60 ± 2.67%

1.05 ± 2.69

0.025

MLS (mm)

6.55 ± 2.87

3.64 ± 3.68

0.054

Hemorrhagic pattern

  

0.819

No hemorrhage

3 (42.9%)

22 (56.4%)

 

HI 1

1 (14.3%)

7 (17.9%)

 

HI 2

1 (14.3%)

4 (10.3%)

 

PH 1

2 (28.6%)

6 (15.4%)

 

PH 2

0 (0.0%)

0 (0.0%)

 
  1. Values are presented as mean ± SD, number (%), or median (interquartile range)
  2. CT Computed tomography angiography, ONSD Optic nerve sheath diameter, ETD Eyeball transverse diameter, MLS Midline shift, HI Hemorrhagic infarct, PH Parenchymal hematoma