Fig. 1

Radiological findings in the course. Brain MRI of hepatits-E-related lesions displayed in a time chart over 11 weeks (from left to right). a Retrobulbar enhancement of nervi optici which shows a regredient state, coronal T1-weighted images with contrast medium. b, c Hypersignal of the brain marrow of the temporal lobe and rostral of the corpus callosum on the left which shows a deterioration in the second picture. After 11 weeks a decline of the lesions were found (FLAIR). d A 10 mm hyperintense lesion at the cervical spine was found and declared as a severe edema which caused swelling. The middle picture shows a significant deterioration of the lesion. The right picture shows a partial decline of the lesion (T2, turbo inversion recovery magnitude (TIRM)-weighted images without contrast medium). e Significant space-consuming hyperintense lesion of the thoracic spine was detected in the first MRI (left picture). Middle picture shows a distinct progredient edema. The right picture shows a significant regression of the pathologies. (TIRM-weighted images without contrast medium). Investigations were performed with 3.0 Tesla, Siemens Magnetom Verio for the left and right pictures and for the middle pictures: 3.0 T Siemens Magnetom Vida was used