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Table 1 Clinical and Demographic Characteristics of Patients with CSDH

From: Elevated blood urea nitrogen is associated with recurrence of post-operative chronic subdural hematoma

Variables

All patients

(N = 653)

Recurrence(n = 96)

Non-Recurrence(n = 557)

P-value

Postoperative BUN (mmol/L)

4.9 (4,6.4)

5.9 (4.4,6.9)

4.9 (3.9,6.3)

< 0.001

Demographic parameters

 Age (years)

72 (64,80)

75 (69,82)

71 (63,80)

0.012

 Gender

   

0.263

  Male, n (%)

561 (85.9%)

86 (89.6%)

475 (85.3%)

 

  Female, n (%)

92 (14.1%)

10 (10.4%)

82 (14.7%)

 

 Current drinking, n (%)

234 (35.8%)

34 (35.4%)

200 (35.9%)

0.926

 Current smoking, n (%)

237 (36.3%)

33 (34.4%)

204 (36.6%)

0.672

 Baseline SBP (mmHg)

138 (126,153)

135 (124,151)

140 (127,153)

0.122

 Baseline DBP (mmHg)

79 (71,87)

77 (71,84)

79 (71,87)

0.091

Laboratory investigation

 Blood glucose (mmol/L)

5.5 (4.7,6.6)

5.7 (5,6.7)

5.4 (4.7,6.6)

0.265

 Cr (μmol/L)

67 (58,77)

68 (60,80)

66 (57,77)

0.097

 Leukocyte (X10^9/L)

6.94 (5.81,8.43)

6.51 (5.52,7.55)

7.01 (5.85,8.62)

0.010

 Neutrophil (X10^9/L)

4.62 (3.68,6.15)

4.30 (3.51,5.31)

4.70 (3.71,6.26)

0.012

 Lymphocyte (X10^9/L)

1.46 (1.10,1.81)

1.46 (1.17,1.83)

1.47 (1.1,1.81)

0.650

 Erythrocyte (X10^12/L)

4.23 ± 0.51

4.19 ± 0.52

4.24 ± 0.51

0.379

 Hemoglobin (g/L)

132 (120,142)

132 (119,142)

132 (119,140)

0.442

 Platelet (X10^9/L)

211 (172,249)

194 (164,239)

213 (175,251)

0.010

 Prothrombin Time(s)

13.3 (12.8,13.9)

13.4 (12.8,14.0)

13.3 (12.8,13.9)

0.642

 INR

1.02 (0.97,1.08)

1.02 (0.98,1.10)

1.02 (0.97,1.07)

0.719

 Fibrinogen (g/L)

3.61 (3.09,4.28)

3.50 (2.89,4.15)

3.64 (3.15,4.30)

0.046

Comorbidities

 Hypertension, n (%)

252 (38.6%)

40 (41.7%)

212 (38.1%)

0.503

 Diabetes mellitus, n (%)

77 (11.8%)

11 (11.5%)

66 (11.8%)

0.913

 Cardiovascular disease, n (%)

42 (6.4%)

6 (6.3%)

36 (6.5%)

0.937

Medication use

 Atorvastatin therapy, n (%)

478 (73.2%)

74 (77.1%)

404 (72.5%)

0.352

 PAMBA therapy, n (%)

189 (28.9%)

26 (27.1%)

163 (29.3%)

0.663

Hematoma location

   

0.957

 Unilateral left, n (%)

288 (44.1%)

42 (43.8%)

246 (44.2%)

 

 Unilateral right, n (%)

216 (33.1%)

31 (32.3%)

185 (33.2%)

 

 Bilateral, n (%)

149 (22.8%)

23 (24.0%)

126 (22.6%)

 

Postoperative bleeding

136 (20.8%)

22 (22.9%)

114 (20.5%)

0.585

GOS at discharge

   

0.549

 5, n (%)

593 (90.8%)

90 (93.8%)

503 (90.3%)

 

 4, n (%)

48 (7.4%)

5 (5.2%)

43 (7.7%)

 

 3, n (%)

12 (1.8%)

1 (1.0%)

11 (2.0%)

 

Preoperative investigation

N = 632

n = 95

n = 537

 

 BUN (mmol/L)

5.3 (4.4,6.5)

5.9 (4.8,6.9)

5.2 (4.3,6.4)

0.001

  1. NOTE. SBP, systolic blood pressure; DBP, diastolic blood pressure; Cr, creatinine; INR, international normalized ratio; PAMBA, para-aminomethylbenzoic acid; BUN, blood urea nitrogen; GOS, Glasgow Outcome Scale