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Table 7 Overall Non-motor Symptoms Composition Across a Three-Year Period

From: Social listening – revealing Parkinson’s disease over day and night

 

Symptom

2016

2017

2018

2016–2018

CAGRa

p-value

Sleep and Sensory Disorders

Pain

24.4%

25.2%

25.8%

+ 2.9%

0.15

Frequent urination

7.5%

8.6%

11.8%

+ 25.8%

< 0.01

Insomnia

6.2%

6.3%

8.9%

+ 20.0%

< 0.01

RBD

3.9%

5.1%

7.4%

+ 37.3%

< 0.01

Poor sleep quality

5.4%

5.6%

5.7%

+ 2.4%

0.34

Excessive Daytime Sleepiness

3.8%

4.1%

5.6%

+ 20.9%

< 0.01

Numbness

4.9%

4.2%

5.0%

+ 1.4%

0.44

Spasm

3.7%

3.8%

3.6%

−1.6%

0.43

Olfactory disorder

0.9%

1.0%

2.5%

+ 64.5%

< 0.01

Cognitive and Psychiatric Disorders

Depression

6.1%

7.0%

11.4%

+ 36.2%

< 0.01

Hallucinations

7.2%

9.1%

10.0%

+ 18.1%

< 0.01

Dementia

5.7%

6.3%

9.1%

+ 26.6%

< 0.01

Anxiety

2.4%

3.3%

6.9%

+ 70.6%

< 0.01

Slow reaction

2.0%

2.0%

3.4%

+ 31.4%

< 0.01

Other psychiatric issues

1.2%

1.1%

1.3%

+ 4.7%

0.39

Autonomic Disorders

Constipation

7.9%

8.4%

12.1%

+ 23.9%

< 0.01

Other gastrointestinal dysfunctions

6.8%

8.3%

8.1%

+ 9.5%

0.06

Drooling

4.9%

4.8%

5.9%

+ 9.6%

0.08

  1. aCAGR Compounded annual growth rate