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Table 8 Nocturnal Motor and Non-motor Symptoms Composition Across a Three-Year Period

From: Social listening – revealing Parkinson’s disease over day and night

Symptom

2016

2017

2018

2016–2018

CAGRa

p-value

Overall Nocturnal Symptoms

39%

41%

45%

+ 6.0%

< 0.01

Rigidity/difficulty turning over

11.9%

12.8%

16.0%

+ 16.0%

< 0.01

Insomnia

6.2%

6.3%

8.9%

+ 20.0%

< 0.01

Night tremor

7.0%

6.8%

8.7%

+ 11.2%

0.02

RBD

3.9%

5.1%

7.4%

+ 37.3%

< 0.01

Nocturnal pain

5.3%

5.9%

7.3%

+ 17.3%

< 0.01

Poor sleep quality

5.4%

5.6%

5.7%

+ 2.4%

0.34

Excessive Daytime Sleepiness

3.8%

4.1%

5.6%

+ 20.9%

< 0.01

Frequent nocturia

2.9%

3.6%

5.3%

+ 35.6%

< 0.01

Hallucinations

1.6%

2.1%

2.5%

+ 26.9%

0.03

Morning pain

0.6%

1.0%

1.4%

+  51.0%

< 0.01

Nocturnal spasm

1.1%

1.0%

1.2%

+  8.2%

0.38

Difficulty breathing

0.3%

0.5%

0.8%

+  52.2%

0.02

  1. aCAGR Compounded annual growth rate