Table 1 Baseline characteristics and neutrophil-to-lymphocyte ratio according to status of ischemic stroke
|  | Total participants included (n = 2989) | All participants with stroke (n = 1867) | All participants without stroke (n = 1122) | P |
|---|---|---|---|---|
Age, mean ± SD, years | 68.03 (11.37) | 67.96 (11.57) | 68.16 (11.04) | 0.717 |
Female | 1165 (38.98) | 658 (35.26) | 507 (45.23) | 0.000* |
SBP, median [IQR], mmHg | 146 [130–160] | 150 [135–165] | 140 [130–155] | 0.000* |
DBP, median [IQR], mmHg | 82 [80–90] | 85 [80–92] | 80 [78–90] | 0.000* |
Hematological examinations | ||||
 Glucose, median (IQR), mmol/L | 5.32 (4.67–6.91) | 5.47 (4.70–7.43) | 5.16 (4.62–6.36) | 0.000* |
 HDL, median (IQR), mmol/L | 1.12 (0.95–1.33) | 1.12 (0.95–1.31) | 1.12 (0.95–1.35) | 0.200 |
 LDL, median (IQR), mmol/L | 2.98 (2.40–3.57) | 3.04 (2.48–3.66) | 2.85 (2.29–3.43) | 0.000* |
 TC, median (IQR), mmol/L | 4.88 (4.10–5.70) | 4.95 (4.17–5.83) | 4.71 (3.97–5.33) | 0.000* |
 TG, median (IQR), mmol/L | 1.29 (0.95–1.76) | 1.30 (0.97–1.78) | 1.27 (0.91–1.73) | 0.035†|
 Neutrophils, median (IQR), (109/L) | 3.83 (2.99–4.96) | 4.05 (3.17–5.36) | 3.49 (2.78–4.37) | 0.000* |
 Lymphocytes, median (IQR), (109/L) | 1.94 (1.52–2.41) | 1.94 (1.52–2.43) | 1.94 (1.51–2.40) | 0.467 |
 NLR, median (IQR) | 1.92 (1.43–2.76) | 2.01 (1.49–3.00) | 1.76 (1.33–2.44) | 0.000* |
Medical history | ||||
 Hypertension, n (%) | 2370 (79.29) | 1476 (79.06) | 894 (79.68) | 0.685 |
 Diabetes mellitus, n (%) | 1079 (36.10) | 694 (37.17) | 385 (34.31) | 0.115 |
 Stroke, n (%) | 711 (23.79) | 449 (24.05) | 262 (23.35) | 0.000* |
 CHD, n (%) | 1141 (38.17) | 628 (33.64) | 513 (45.72) | 0.000* |
Smoking, n (%) | 1015 (33.96) | 690 (36.96) | 325 (28.97) | 0.000* |
Drinking, n (%) | 716 (23.95) | 492 (26.35) | 224 (19.96) | 0.000* |
ICAS, n (%) | 851 (28.47) | 612 (32.78) | 239 (21.30) | 0.000* |