Table 4 Demographics and clinical data of patients with positive and negative AQP4-IgG status
Positive (n = 35) | Negative/Unavailable (n = 35) | P-value | |
|---|---|---|---|
Age (Mean ± SD) | 34.9 ± 9.1 | 34.8 ± 9.5 | 0.20 |
Sex F/M (n) | 29/6 | 29/6 | 1.00 |
Age at onset (Mean ± SD) | 30.1 ± 9.3 | 27.6 ± 11.5 | 0.30 |
Number of relapses (Mean ± SD) | 4.4 ± 2.3 | 3.8 ± 2.4 | 0.30 |
Presentation | |||
Monosymptomatic (n) | 30 | 29 | 0.50 |
Polysymptomatic (n) | 5 | 6 | |
Initial monosymptomatic presentation (n) | |||
Brain stem syndrome | 5 | 1 | 0.30 |
Transverse myelitis | 11 | 16 | |
Optic neuritis | 13 | 12 | |
Area postrema syndrome | 1 | 0 | |
Baseline EDSS (Mean ± SD) | 5.1 ± 2.2 | 4.2 ± 2.3 | 0.09 |
Last assessed EDSS (Mean ± SD) | 5.1 ± 2.3 | 4.3 ± 2.1 | 0.08 |