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Table 3 Baseline characteristics and outcomes according to functional outcomes at 3 months of cancer-related stroke

From: Effectiveness of mechanical thrombectomy in cancer-related stroke and associated factors with unfavorable outcome

Characteristics

Favorable outcome

Unfavorable outcome

p value

3-Month mRS score 0–2

3-Month mRS score 3–6

Total

N = 11

N = 23

 

Age, year, median (IQR)

70 (57–73.50)

65 (59–72.50)

0.690

Male

9 (81.8%)

8 (34.7%)

0.026

Pre mRS score, median (IQR)

0 (0–0)

0 (0–2.5)

0.153

Initial NIHSS score, median (IQR)

9 (7.5–13.5)

20 (17–25)

< 0.001

Vascular risk factors

 Prior stroke or TIA

4 (36.3%)

2 (8.7%)

0.070

 Coronary artery disease

1 (9.1%)

4 (17.4%)

0.507

 Hypertension

7 (63.6%)

15 (65.2%)

0.928

 Diabetes mellitus

4 (36.4%)

8 (34.8%)

0.928

 Dyslipidemia

4 (36.4%)

9 (39.1%)

0.878

 Smoking

3 (27.3%)

2 (8.7%)

0.300

Previous use of antithrombotics†

4 (30.8%)

9 (39.1%)

0.876

Administration of IV-rtPA

1 (9.1%)

8 (34.8%)

0.214

Occlusion site

  

0.861

 Middle cerebral artery, M1

5 (45.4%)

13 (56.5%)

 

 Middle cerebral artery, M2

2 (18.2%)

4 (17.4%)

 

 Internal carotid artery

3 (27.3%)

2 (8.7%)

 

 Anterior cerebral artery

0 (0%)

1 (4.3%)

 

 Posterior cerebral artery/Basilar artery

1 (9.1%)

3 (13.1%)

 

In-Hospital Stroke

4 (36.4%)

7 (30.4%)

0.731

Time variables

 Onset-to-puncture time, min, SD

471 (290.24)

364.39 (224.31)

0.612

 Puncture-to-reperfusion time, min, SD

74.45 (27.48)

80.17 (46.13)

0.856

Radiologic Outcomes

 Recanalization status

  

0.160

  mTICI 3, 2b

11 (100%)

16 (69.6%)

 

  mTICI 2a

0 (0%)

5 (21.7%)

 

  mTICI 1, 0

0 (0%)

2 (8.7%)

 

Any cerebral hemorrhage

1 (9.1%)

13 (56.5%)

< 0.001

 Cancer by location

  

0.510

  Pancreatic cancer

2 (18.2%)

7 (30.4%)

 

  Lung cancer

4 (36.4%)

3 (13.0%)

 

  Bile duct cancer

2 (18.2%)

3 (13.0%)

 

  Liver cancer

1 (9.1%)

2 (8.7%)

 

  Gastric cancer

0 (0%)

2 (8.7%)

 

  Colon cancer

1 (9.1%)

2 (8.7%)

 

  Ovarian cancer

1 (9.1%)

2 (8.7%)

 

  Breast cancer

0 (0%)

2 (8.7%)

 

 Cancer stage

  

0.018

  III

7 (63.6%)

5 (21.7%)

 

  IV

4 (36.4%)

18 (78.3%)

 

 Cancer type

  

0.280

  Adenocarcinoma

11(100%)

19 (82.6%)

 

  Others

0 (0%)

4(17.4%)

 

Systemic metastasis

4 (36.4%)

18 (78.3%)

0.016

D-dimer, median (IQR)

10.7 (6.66–17.71)

16.95 (14.55–26.60)

0.028

  1. Abbreviations: mRS modified Rankin scale, IQR interquartile range, NIHSS National institute of health stroke scale, TIA transient ischemic attack, IV intravenous, rtPA recombinant tissue plasminogen activator, mTICI modified thrombolysis in cerebral infarction
  2. †Antiplatelets and anticoagulation agents