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Table 3 Baseline characteristics and outcomes according to functional outcomes at 3 months of cancer-related stroke

From: Effectiveness of mechanical thrombectomy in cancer-related stroke and associated factors with unfavorable outcome

Characteristics Favorable outcome Unfavorable outcome p value
3-Month mRS score 0–2 3-Month mRS score 3–6
Total N = 11 N = 23  
Age, year, median (IQR) 70 (57–73.50) 65 (59–72.50) 0.690
Male 9 (81.8%) 8 (34.7%) 0.026
Pre mRS score, median (IQR) 0 (0–0) 0 (0–2.5) 0.153
Initial NIHSS score, median (IQR) 9 (7.5–13.5) 20 (17–25) < 0.001
Vascular risk factors
 Prior stroke or TIA 4 (36.3%) 2 (8.7%) 0.070
 Coronary artery disease 1 (9.1%) 4 (17.4%) 0.507
 Hypertension 7 (63.6%) 15 (65.2%) 0.928
 Diabetes mellitus 4 (36.4%) 8 (34.8%) 0.928
 Dyslipidemia 4 (36.4%) 9 (39.1%) 0.878
 Smoking 3 (27.3%) 2 (8.7%) 0.300
Previous use of antithrombotics† 4 (30.8%) 9 (39.1%) 0.876
Administration of IV-rtPA 1 (9.1%) 8 (34.8%) 0.214
Occlusion site    0.861
 Middle cerebral artery, M1 5 (45.4%) 13 (56.5%)  
 Middle cerebral artery, M2 2 (18.2%) 4 (17.4%)  
 Internal carotid artery 3 (27.3%) 2 (8.7%)  
 Anterior cerebral artery 0 (0%) 1 (4.3%)  
 Posterior cerebral artery/Basilar artery 1 (9.1%) 3 (13.1%)  
In-Hospital Stroke 4 (36.4%) 7 (30.4%) 0.731
Time variables
 Onset-to-puncture time, min, SD 471 (290.24) 364.39 (224.31) 0.612
 Puncture-to-reperfusion time, min, SD 74.45 (27.48) 80.17 (46.13) 0.856
Radiologic Outcomes
 Recanalization status    0.160
  mTICI 3, 2b 11 (100%) 16 (69.6%)  
  mTICI 2a 0 (0%) 5 (21.7%)  
  mTICI 1, 0 0 (0%) 2 (8.7%)  
Any cerebral hemorrhage 1 (9.1%) 13 (56.5%) < 0.001
 Cancer by location    0.510
  Pancreatic cancer 2 (18.2%) 7 (30.4%)  
  Lung cancer 4 (36.4%) 3 (13.0%)  
  Bile duct cancer 2 (18.2%) 3 (13.0%)  
  Liver cancer 1 (9.1%) 2 (8.7%)  
  Gastric cancer 0 (0%) 2 (8.7%)  
  Colon cancer 1 (9.1%) 2 (8.7%)  
  Ovarian cancer 1 (9.1%) 2 (8.7%)  
  Breast cancer 0 (0%) 2 (8.7%)  
 Cancer stage    0.018
  III 7 (63.6%) 5 (21.7%)  
  IV 4 (36.4%) 18 (78.3%)  
 Cancer type    0.280
  Adenocarcinoma 11(100%) 19 (82.6%)  
  Others 0 (0%) 4(17.4%)  
Systemic metastasis 4 (36.4%) 18 (78.3%) 0.016
D-dimer, median (IQR) 10.7 (6.66–17.71) 16.95 (14.55–26.60) 0.028
  1. Abbreviations: mRS modified Rankin scale, IQR interquartile range, NIHSS National institute of health stroke scale, TIA transient ischemic attack, IV intravenous, rtPA recombinant tissue plasminogen activator, mTICI modified thrombolysis in cerebral infarction
  2. †Antiplatelets and anticoagulation agents