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Table 2 Classification of complications

From: Outcome registry of early intensive neurorehabilitation in patients with disorders of consciousness: study protocol of a prospective cohort study

• Mental/nervous system
o Epilepsy
o Hydrocephalus
o Paroxysmal Sympathetic Hyperactivity (PSH)
o Disturbed sleep/wake cycles
• Sensory systems
• Cardiovascular, haematologic, immunologic and respiratory systems
o Thromboembolic disease
o Abnormal laboratory findings (e.g. hyponatremia)
• Digestive, metabolic and endocrine systems
o Gastro-intestinal: vomiting, diarrhoea, obstipation
• Genitourinary and reproductive systems
• Musculoskeletal and movement-related systems
o Contractures measured by joint range of motion (ROM)
o Spasticity: Modified Ashworth scale
o Heterotopic ossification
• Skin and related structures
o Skin breakdown: EPUAP stages I-IV (Dutch guideline: pressure ulcer: prevention and treatment [27]
• Infection
 Body system
  o Respiratory
  o Urinary tract
  o Blood
  o Stool
  o CSF, brain
  o Wound/skin
  o Ear/eye
 Antibiotic-resistant bacteria