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Table 3 GMDR Analysis on the Best SNP-SNP Interaction Combinations

From: Single nucleotide polymorphisms in the ANGPTL4 gene and the SNP-SNP interactions on the risk of atherosclerotic Ischaemic stroke

Locus no.

Best combination

Testing accuracy

Cross Validation

consistency

P-valuea

2

rs11672433, rs4076317

0.5796

10/10

0.0010

3

rs11672433, rs4076317, rs1044250

0.5870

10/10

0.0647

  1. P-values less than 0.05 were considered statistically significant. Abbreviations: GMDR generalized multifactor dimensionality reduction; SNP single-nucleotide polymorphism
  2. a Adjusted for gender, age, smoking and alcohol status, hypertension, diabetes mellitus, TG, TC, HDL-C, LDL-C, Uric acid