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Table 1 Demographic features of ischemic stroke patients with high-grade carotid artery stenosis

From: Association between estimated glomerular filtration rate and clinical outcomes in ischemic stroke patients with high-grade carotid artery stenosis

 

eGFR (mL/min/1.73 m2)

 
 

<  45

(n = 76)

45–59

(n = 65)

≥ 60

(n = 231)

P

Age (years)

77 (71–82)

75 (70–81)

70 (61–79)

< 0.001*

Male (%)

48 (63.2)

44 (67.7)

181 (78.4)

0.018†

Risk factors

  

 Hypertension (%)

72 (94.7)

53 (81.5)

186 (80.5)

0.013†

 Diabetes mellitus (%)

46 (60.5)

29 (44.6)

100 (43.3)

0.030†

 Smoking (%)

45 (59.2)

40 (61.5)

161 (69.7)

0.170

 Hyperlipidemia (%)

43 (56.6)

43 (66.2)

143 (61.9)

0.500

 Atrial fibrillation (%)

18 (24.0)

11 (16.9)

35 (15.2)

0.211

 CAD (%)

26 (34.2)

15 (23.1)

34 (14.7)

0.001†

 CHF (%)

20 (26.3)

8 (12.3)

13 (5.6)

< 0.001†

 Valvular heart disease (%)

4 (5.3)

3 (4.6)

2 (0.9)

0.043†

 Peripheral vascular disease (%)

3 (3.9)

2 (3.1)

4 (1.7)

0.513

 Gout (%)

34 (44.7)

17 (26.2)

28 (12.1)

< 0.001†

Clinical syndromes

  

 TACI (%)

13 (17.1)

14 (21.5)

44 (19.0)

0.800

 PACI (%)

31 (40.8)

25 (38.5)

87 (37.7)

0.889

 LACI (%)

28 (36.8)

20 (30.8)

80 (34.8)

0.743

Laboratory data

 Hemoglobin (mmol/L)

7.63 (6.83–8.32)

8.32 (7.63–9)

8.63 (7.88–9.37)

< 0.001*

 WBC (109/ L)

7.60 (6.20–9.78)

7.60 (5.95–9.45)

7.90 (6.30–9.50)

0.670

 Platelet (109/ L)

204 (167–268)

193 (160–261)

208 (175–255)

0.604

 Glycohemoglobin (%)

6.3 (5.8–7.3)

6.1 (5.8–7.0)

6.0 (5.7–6.9)

0.279

 hs-CRP (nmol/L)

57.1 (27.6–160)

47.2 (28.6–91.4)

42.9 (21.0–85.7)

0.081

 Total cholesterol (mmol/L)

4.60 (3.62–5.48)

4.81 (4.27–6)

4.89 (4.29–5.56)

0.048*

 Na (mmol/L)

138 (136–140)

138 (136–140)

138 (136–140)

0.710

 K (mmol/L)

4.1 (3.8–4.6)

3.9 (3.6–4.2)

3.9 (3.6–4.1)

< 0.001*

 Uric acid (mmol/L)

0.41 (0.36–0.48)

0.35 (0.29–0.40)

0.34 (0.28–0.39)

< 0.001*

Antithrombotic treatment

 Aspirin (%)

41 (53.9)

47 (72.3)

159 (68.8)

0.032†

 Clopidogrel (%)

26 (34.2)

11 (16.9)

54 (23.4)

0.048†

 Anticoagulant (%)

9 (11.8)

9 (13.8)

30 (13.0)

0.938

 None (%)

3 (3.9)

2 (3.1)

2 (0.9)

0.032†

  1. eGFR indicates estimated Glomerular filtration rate; CAD coronary artery disease; CHF congestive heart failure; TACI total anterior circulation infarcts; PACI partial anterior circulation infarcts; LACI lacunar infarcts; WBC white blood cells; hs-CRP high-sensitivity C-reactive protein
  2. Data are presented as median (interquartile range) or absolute numbers (percentage)
  3. *P < 0.05, Kruskal-Wallis test; †P < 0.05, Chi-square test