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Table 3 Demographic characteristic and biochemical analysis in MS and control sub-groups

From: Reduction in circulating vitamin D binding protein in patients with multiple sclerosis

Demographic characteristic

MS (N = 77)

Control (N = 67)

p-value

Age (years)†

33.68 ± 8.16

34.71 ± 6.45

0.89

Sex (Women)‡

76.9% (60)

76.6% (52)

0.94

BMI (kg/m2)†

24.66 ± 4.47

24.19 ± 3.81

0.49

Clinical outcomes

 MS Duration (month)††

4.02 (8)

–

 

 MS diagnosis age (years)†

33.60 ± 7.81

–

 

 Smoking‡

10.0% (7)

6.0% (4)

0.52

 Vitamin D levels†

33.60 ± 14.91

21.55 ± 12.49

0.0001

 Ln. VDBP levels (μgr/ml) †

3.64 ± 0.91

5.31 ± 0.77

0.0001

Albumin (g/dl)†

4.07 ± 0.81

4.10 ± 0.85

0.89

Taking vitamin D supplement ‡

 Regular

54.5% (42)

18.0% (12)

0.0001

 Irregular

17.0% (13)

35.8%(24)

 Never

28.5% (22)

46.2% (31)

Taking drug at the sampling time‡

No treatment

32.5% (25)

–

 

Rituximab

11.7% (9)

–

 

Natalizumab

2.6%(2)

–

 

 Interferon B1a

26.0% (20)

–

 

 Glatiramer acetate

9.1% (7)

–

 

 Dimethyl fumarate

2.6% (2)

–

 

 4 Aminopyridin

1.3% (1)

–

 

 Fingolimod

13.0% (10)

–

 

 Teriflunomide

1.3% (1)

–

 

 Corticosteroids

–

–

 
  1. Abbreviations: BMI body mass index, Ln natural logarithm
  2. †mean ± SD, †† median (IQR), ‡%(N)