Table 1 Demographic and clinical features of the MSA patients with and without camptocormia

Number

716

90 (12.6%)

626 (87.4%)

–

Diagnosis (MSA-P/MSA-C)

352/364

60/30

292/334

< 0.001*

Sex (male/female)

405/311

46/44

359/267

0.264

Age

60.18 ± 8.99

63.73 ± 7.91

59.67 ± 9.03

< 0.001*

Age of onset

57.54 ± 8.94

60.53 ± 7.81

57.11 ± 9.02

0.001*

Disease duration

2.59 ± 1.69

3.18 ± 1.67

2.50 ± 1.67

< 0.001*

Educational year

9.46 ± 3.92

9.21 ± 4.16

9.49 ± 3.89

0.522

Onset symptoms

Autonomic symptom

247

28

219

0.005*

Cerebellar symptom

198

15

183

Parkinsonism symptom

271

47

224

UMSARS-I

14.30 ± 6.68

17.97 ± 7.43

13.77 ± 6.40

< 0.001*^#

UMSARS-II

16.98 ± 6.95

21.89 ± 7.60

16.28 ± 6.56

< 0.001*^#

UMSARS-IV

2.00 ± 0.96

2.68 ± 1.17

1.90 ± 0.88

< 0.001*^#

Total UMSARS score

31.28 ± 12.80

39.86 ± 14.22

30.04 ± 12.11

< 0.001*^#

OH (yes/no)

198/518

28/62

170/456

0.433

Total score of FAB

14.32 ± 2.96

13.52 ± 3.47

14.44 ± 2.87

0.006*

Total MOCA score

21.57 ± 5.06

20.71 ± 6.00

21.70 ± 4.91

0.084

HDRS score

11.47 ± 8.03

13.57 ± 9.09

11.16 ± 7.83

0.008*

HARS score

9.52 ± 7.02

10.11 ± 7.27

9.43 ± 6.98

0.392

LEDD (mg/day)

137.40 ± 243.00

209.58 ± 270.48

127.02 ± 237.22

0.001*