Table 1 Summary of Chinese patients with DOCK8 mutation
Index Case | Sex | Mutation | Clinic feature | |||
|---|---|---|---|---|---|---|
Infection | Allergy | Atopic dermatitis | Eczema | |||
1 | F | c.1126_1285del | Yes | Yes | Yes | No |
2 | M | c.646_647del | Yes | Yes | Yes | No |
3 | M | c.646_647del | No | No | Yes | No |
4 | F | c.5842delG, c.5843C > A | Yes | Yes | No | Yes |
5 | M | Exon11 hom del Exon 12–33 het del | Yes | Yes | No | Yes |
6 | F | c.3152delG | Yes | Yes | No | Yes |
7 | F | c.3152delG | Yes | Yes | No | Yes |
8 | F | Exon 2 hom del Exon 1, 3–39 het del | Yes | Yes | No | Yes |
9 | F | Exon 7 hom del Exon 8–10 het del | Yes | Yes | No | Yes |
10 | M | c.1278–1279 del TG | Yes | Yes | No | Yes |
11 | F | c.4886 G > A | Yes | No | No | Yes |