Validity and reliability of the medial temporal lobe atrophy scale in a memory clinic population

BMC Neurology

Table 2 Bilateral mean MTA score and hippocampal volume in patient groups

	N	Mean MTA score	N	Manual volumetry (mm³)	N	FreeSurfer volumetry (mm³)
CH	105	0.53 (0.46)	34	2201 (310)	57	3874 (475)
SCI	184	0.71 (0.63)*	6	2283 (393)	158	3699 (466)*
MCI	249	0.95 (0.76)†	63	2211 (360)	163	3477 (565)†
Dementia
AD	98	1.71 (0.89)†	13	1954 (310)*	76	2871 (552)†
SVD	25	1.22 (0.68)†	6	2352 (199)	15	3477 (376)*
Mixed	51	1.64 (0.89)†	9	1936 (310)*	37	2809 (547)†

Data are given as mean of right and left sides (SD)
In participants with dementia other than AD, SVD or Mixed, manual volumetry was performed in three MRI exams and FreeSurfer volumetry in 34 MRI exams
AD Alzheimer’s disease, CH Cognitively healthy, MCI Mild cognitive impairment, Mixed Mixed dementia, MTA Medial temporal lobe atrophy, SCI Subjective cognitive impairment, SVD Subcortical vascular dementia
* Significant results compared to CH, p < 0.05. † Significant results compared to CH, p < 0.001

ISSN: 1471-2377