Expression of and correlational patterns among neuroinflammatory, neuropeptide, and neuroendocrine molecules from cerebrospinal fluid in cerebral palsy

Table 2 Significant Pearson’s correlations (p ≤ 0.001) between analyte pairs, representing 21 distinct analyte correlations (bold font)

Analyte 1	Analyte 2	Correlation	95% CI	Adj. p
Dynorphin A	AGRP	0.71	[0.34, 0.85]	< .001
Dynorphin A	ACTH	0.79	[0.60, 0.90]	< .001
Dynorphin A	IL-12p70	0.68	[0.41, 0.84]	0.001
Dynorphin A	TNFα	0.80	[0.60, 0.90]	< .001
Dynorphin A	substance P	0.78	[0.57, 0.89]	< .001
AGRP	IL-6	0.73	[0.49, 0.87]	< .001
AGRP	IL-8	0.71	[0.46, 0.86]	< .001
AGRP	IL-10	0.91	[0.81, 0.96]	< .001
AGRP	IL-12p40	0.73	[0.50, 0.87]	< .001
AGRP	MIP-1β	0.94	[0.87, 0.97]	< .001
AGRP	TNFα	0.67	[0.40, 0.84]	0.001
FSH	LH	0.89	[0.78, 0.95]	< .001
TSH	ACTH	0.69	[0.42, 0.84]	0.001
ACTH	IL-12p70	0.82	[0.65, 0.92]	< .001
ACTH	TNFα	0.92	[0.83, 0.96]	< .001
ACTH	β endorphin	0.67	[0.40, 0.83]	0.001
ACTH	substance P	0.91	[0.81, 0.96]	< .001
IFNα2	IL-12p70	0.73	[0.49, 0.87]	< .001
IL-1α	IL-12p40	0.78	[0.57, 0.89]	< .001
IL-1α	IP-10	0.79	[0.60, 0.90]	< .001
IL-1RA	orexin A	0.75	[0.52, 0.88]	< .001
IL-6	IL-10	0.87	[0.74, 0.94]	< .001
IL-6	IL-12p40	0.68	[0.41, 0.84]	0.001
IL-8	MIP-1β	0.73	[0.49, 0.87]	< .001
IL-10	IL-12p40	0.74	[0.51, 0.87]	< .001
IL-10	MIP-1β	0.81	[0.63, 0.91]	< .001
IL-12p40	IP-10	0.81	[0.63, 0.91]	< .001
IL-12p70	TNFα	0.91	[0.81, 0.96]	< .001
IL-12p70	substance P	0.82	[0.64, 0.91]	< .001
TNFα	substance P	0.93	[0.86, 0.97]	< .001
β endorphin	orexin A	0.81	[0.63, 0.91]	< .001
β endorphin	substance P	0.81	[0.62, 0.91]	< .001
β endorphin	αMSH	0.70	[0.44, 0.85]	0.001
orexin A	substance P	0.70	[0.44, 0.85]	0.001
orexin A	αMSH	0.79	[0.58, 0.90]	< .001

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