Associations of the cerebrospinal fluid hepatocyte growth factor with Alzheimer’s disease pathology and cognitive function

Table 1 Demographic characteristics for all the participants

Characteristics	CN	MCI	P
N	90	148
Age (Mean ± SD, year)	75.60 ± 5.46	74.82 ± 7.21	0.353
Sex (Female, %)	45 (50)	47 (31.8)	0.005
Education (Mean ± SD, year)	15.57 ± 2.94	15.96 ± 2.94	0.284
APOE ε4 carrier status (Yes, %)	22 (24.4)	79 (53.4)	< 0.0001
WMHV (Mean ± SD, cm³)	0.77 ± 1.93	0.82 ± 2.64	0.894
CSF HGF (Mean ± SD, ng/ml)	0.39 ± 0.15	0.45 ± 0.17	0.006

ANOVA, non-parametric Kruskal-Wallis H test, and Chi-squared test were used to compare the baseline demographic and clinical characteristics. Abbreviations: CN cognitively normal; MCI mild cognitive impairment; WMHV white matter hyperintensities volume; CSF cerebrospinal fluid; HGF Hepatocyte Growth Factor

ISSN: 1471-2377