Association between the HLA-B*1502 gene and mild maculopapular exanthema induced by antiepileptic drugs in Northwest China

Table 2 Binary logistic regression analysis of different factors contributing to AED-MPE¹

variable	B²	P² value	Crude OR,95 % CI	Adjusted OR,95 % CI
age	0.013	0.493	1.014(0.976–1.053)	1.013(0.976–1.052)
sex	-0.078	0.919	1.120(0.270–4.652)	0.925(0.206–4.158)
ethnicity
Han	-	0.664	-	-
Uygur	-0.556	0.559	0.530(0.122–2.312)	0.573(0.089–3.697)
Kazak	-0.888	0.443	0.469(0.052–4.216)	0.412(0.043–3.979)
HLA-B*1502 gene³	2.400	0.028^*	9.333(1.140-76.412)	11.028(1.296–93.818)
region⁴	-0.317	0.737	1.152(0.277–4.782)	0.728(0.114–4.650)
constant	-4.625	0.001	-	0.010

¹AED-MPE: antiepileptic drug-induced maculopapular exanthema
²B: the regression coefficient after eliminating confounding factors.P:P value after eliminating confounding factors
³HLA-B*1502 gene: positive
⁴ Region: Northern Xinjiang region of China, Southern Xinjiang region of China

ISSN: 1471-2377