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Table 2 Comparison of results of each variable pre- and post-isolation period. Data are given as median values with 1st and 3rd quartiles (25- and 75-percentile, respectively Q1 and Q3)

From: Impact of social and mobility restrictions in Parkinson’s disease during COVID-19 lockdown

  Pre-isolation
Median (Q1; Q3)
Post-isolation
Median (Q1; Q3)
Cohen dz Achieved Powerc p-valuea,b
BMI (kg/m2) 26.5 (23.0; 29.6) 27.4 (23.2; 29.6) 0.703 0.841 0.031bd
MDS-UPDRS Part III 14.5 (11.8; 21.3) 19 (12.8; 31.0) 0.513 0.651 0.092a
Mini-BESTest 23 (21.0; 25.5) 19 (16.3; 21.0) 0.994 0.974 0.005bd
6MWT (m) 565.5 (370.8; 660.6) 510.0 (405.0; 665.0) 0.027 0.201 0.799b
NFOG-Q 6.0 (0.0; 13.8) 8.5 (0.0; 15.5) 0.353 0.454 0.313a
MoCA (corrected score) 24.2 (21.7; 26.0) 24.5 (23.3; 26.0) 0.257 0.345 0.392b
PD-CFRS 0.5 (0.0; 1.0) 1.0 (0.8; 1.0) 0.677 0.821 0.123a
IADL 5 (5.0; 6.3) 5 (5.0; 6.3)    
ADL 6.0 (6.0; 6.0) 6.0 (6.0; 6.0)    
PDQ-39 30.5 (17.0; 45.3) 32.5 (20.0; 44.3) 0.215 0.304 0.472b
  1. Note. aWilcoxon signed-rank test or bt-test for continuous variable and McNemar test for discrete variable. MDS-UPDRS Part III = MDS-Unified Parkinson Disease Rating Scale - part III; Mini-BESTest = Mini-Balance Evaluation Systems Test. 6MWT = Six-minute walk test; NFOG-Q = New Freezing of Gait Questionnaire. MoCA = Montreal Cognitive Assessment scale; PD-CFRS = Parkinson’s disease cognitive functional rating scale; ADL = Activities of Daily Living questionnaire; IADL = Instrumental Activities of Daily Living questionnaire; BMI = Body Mass Index; PDQ-39 = Parkinson’s disease Quality of Life Questionnaire. cPost-hoc power analysis. Achieved power was calculated based on Cohen’s dz and an α error probability of 0.2
  2. dSignificant isolation period effect (pre vs. post-isolation evaluation)