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Table 2 Baseline characteristics of the patients with PD-MCI and PD-CN

From: Impairment of the visuospatial working memory in the patients with Parkinson’s Disease: an fMRI study

 

PD-MCI

PD-CN

 
 

n = 13

n = 15

P value

Age

69.4 ± 2.8

67.3 ± 4.6

 N.S.

Men

8

10

 N.S.

Disease Duration (year)

5.0 ± 3.2

5.4 ± 3.5

 N.S.

HY stage

2.1 ± 0.8

2.1 ± 0.7

 N.S.

UPDRS part3

19.8 ± 8.6

10.1 ± 5.2

P < 0.001

L-DOPA (mg)

262 ± 153

223 ± 90

 N.S.

LEDD (mg)

296 ± 199

287 ± 151

 N.S.

MMSE

26.9 ± 1.8

28.1 ± 1.9

 N.S.

MoCA

21.1 ± 3.0

24.3 ± 2.8

P < 0.01

TMT-A (second)

65.6 ± 21.0

43.8 ± 11.2

P < 0.01

TMT-B (second)

276 ± 107.5

111 ± 50.4

P < 0.001

PASAT

21.2 ± 6.1

27.2 ± 6.2

P < 0.05

AVLT (delayed recall)

5.5 ± 3.2

9.1 ± 2.9

P < 0.01

AVLT (word list learning)

4.2 ± 2.5

7.5 ± 2.2

P < 0.01

Verbal fluency (words)

12.0 ± 2.9

15.5 ± 3.1

P < 0.01

Clock Drawing Test

8.8 ± 1.3

9.3 ± 0.8

 N.S.

0-back test (%)

79.2 ± 18.5

89.3 ± 15.2

 N.S.

1-back test (%)

56.5 ± 20.4

71.7 ± 24.9

 N.S.

2-back test (%)

45.8 ± 20.4

63.7 ± 18.3

P < 0.05

  1. HY stage Hoehn and Yahr stage; UPDRS part3 motor sections of United Parkinson’s Disease Rating Scale; LEDD L-dopa equivalent daily dose of dopamine agonist. Calculation of LEDD for each patient was based on theoretical equivalence to L-dopa as follows: L-dopa dose + L-dopa dose × 1/3 [if on entacapone + bromocriptine (mg) ×10 + cabergoline or pramipexole (mg) ×67 + ropinirole (mg) ×20 + pergolide (mg) ×100 + apomorphine (mg) ×8]. MoCA, Montreal Cognitive Assessment, PASAT, Paced Auditory Serial Addition Test; AVLT, Auditory Visual Learning Test; N.S., not significant