Table 3 Logistic regression analyses

Primary outcome

  Median age (IQR)-yr

1.00(0.98–1.01)

0.553

  Male sex- no. (%)

1.11(0.75–1.65)

0.602

  mRS score of 0 ~ 2 before stroke onset-no. (%)

2.14(0.91–5.03)

0.082

  Median glucose level at hospital arrival (IQR) -mmol/L

0.98(0.91–1.06)

0.608

Cause of stroke - no. (%)

  Intracranial atherosclerosis

1

  Cardioembolism

0.90(0.58–1.41)

0.648

  Small-vessel occlusion

0.63(0.37–1.08)

0.095

  Undetermined

0.73(0.33–1.59)

0.430

  History of ischemic stroke

0.43(0.23–0.81)

0.009

  History of atrial fibrillation

0.68(0.45–1.04)

0.075

  History of diabetes mellitus

0.85(0.55–1.34)

0.490

  History of hypertension

0.94(0.61–1.43)

0.763

  From stroke onset to hospital admission

1.00(1.00-1.01)

0.033

  From hospital admission to intravenous alteplase

0.97(0.96–0.98)

< 0.001

  From stroke onset to intravenous alteplase

1.00(1.00–1.00)

0.789

  Median NIHSS score (IQR) before IVT

1.01(0.97–1.04)

0.760

  Treated with embolectomy no. (%)

1.18(0.79–1.77)

0.414

  mRS at 90 days

0.84(0.76–0.93)

0.001

0.87(0.78–0.97)

0.016

Secondary outcomes

    Clinical outcomes

      mRS score at 90 days according to range

      0–1

1.53(1.03–2.25)

0.034

1.27(0.82–1.96)

0.280

      0–2

0.67(0.46-1.00)

0.047

1.26(0.82–1.94)

0.294

      0–3

1.81(1.16–2.83)

0.009

1.61(0.97–2.67)

0.067

      0–4

3.35(1.81–6.21)

< 0.001

3.04(1.57–5.90)

0.001

      0–5

2.57(1.28–5.16)

0.008

2.39(1.14–5.02)

0.021

Early neurological improvement

  1 h after IVT

1.39(0.86–2.25)

0.179

1.37(0.82–2.29)

0.227

  24 h after IVT

1.38(0.93–2.04)

0.111

0.73(0.48–1.11)

0.146

  3d after IVT

1.28(0.87–1.89)

0.205

1.32(0.88–1.98)

0.183

  7d after IVT

0.95(0.63–1.44)

0.814

0.91(0.59–1.41)

0.680

  Death

0.39(0.19–0.78)

0.008

0.42(0.20–0.88)

0.021