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Table 4 Multivariate logistic regression analysis between ΔLDL-C and poor functional outcomea

From: Association between low-density cholesterol change and outcomes in acute ischemic stroke patients who underwent reperfusion therapy

Variable

Non-adjusted model

Adjusted model 1

Adjusted model 2

ΔLDL-C, mmol/l

1.55(1.12, 2.15),0.009

1.79(1.11, 2.89),0.017

1.80(1.12, 2.91),0.016

ΔLDL-C tertiles, mmol/l

 T1 (-0.91-0.13)

Reference

Reference

Reference

 T2 (0.14–0.79)

1.03(0.65, 1.64),0.888

1.23(0.70, 2.18),0.473

1.24(0.70, 2.19),0.470

 T3 (0.80–3.98)

1.92(1.15, 3.20),0.012

2.56(1.22, 5.35),0.013

2.56(1.22, 5.36),0.013

P-trend

0.007

0.010

0.010

  1. Adjusted model 1: adjusted for age, sex, atrial fibrillation, Current smoking, drinking consumption, baseline NIHSS score, Serum glucose, TOAST classification, reperfusion therapy method, and interval between admission and follow-up measurement of LDL-C
  2. Adjusted model 2: adjusted for variables in model 1 and statin use during hospitalization
  3. LDL-C low-density lipoprotein cholesterol, ΔLDL-C the change of low-density lipoprotein cholesterol during hospitalization, NIHSS National Institutes of Health Stroke Scale, TOAST the Trial of Org 10,172 in Acute Stroke Treatment
  4. aResults for each model are presented as odds ratio (95 % confidence interval), p-value