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Table 1 Clinical data of the patients with RESLES

From: Reversible splenial lesion syndrome with mental disorders as only manifestation

Patient ID

Age/ gender

Clinical symptoms

Clinical diagnosis

Treatment

Outcome (hospital stays, days)

1

34/M

alcohol dependence/refusal of food intake/depressive

Alcohol dependence with withdrawal

Diazepam/ Oxazepam/ Mirtazapine/ Vitamin B complex

CR (13)

2

26/M

alcohol dependence/depressive/auditory hallucination/delusion

Alcohol dependence with alcohol-induced psychotic disorder

Diazepam/ Paliperidone/ Valproate/ Vitamin B complex

CR (9)

3

28/M

sensitive/suspicious/loneliness/impaired personal hygiene/irregular intake

Asperger’s syndrome

Aripiprazole/ Mirtazapine/ Vitamin B complex

PR (27d)

4

14/M

behavioral abnormalities/irrelevant talking/auditory hallucination

Other specified mental disorders due to known physiological condition

Olanzapine/ Clonazepam

T/CR (5d)

5

51/F

delusion/ auditory hallucination/ depressive

Other specified mental disorders due to known physiological condition

Quetiapine/ Lorazepam

T/PR (2d)

6

20/F

stupor/depressive

Major depressive disorder, single episode, severe with psychotic features

Quetiapine/ Escitalopram

T/PR (2d)

7

28/F

depressive/behavioral abnormalities/

irrelevant talking/disturbed sleep

Dissociative and conversion disorders

Olanzapine

PR (26d)

8

27/M

persistent headache/

undifferentiated somatoform disorder

Duloxetine / Valproate / Olanzapine

PR (43d)

9

28/M

delusion/behavioral abnormalities/disturbed sleep

Unspecified psychosis not due to a substance or known physiological condition

Ziprasidone / Quetiapine

PR (26)

10

31/F

elevated mood/decreased need for sleep/greater talkativeness

Bipolar disorder, current episode manic severe with psychotic features

Quetiapine/ Lithium carbonate

PR (14d)

  1. MBD Marchiafava-Bignami disease; CR completely recovered. T Transferred to other hospital; PR partial recovered; F female; M male