Gene | SNPs | Genotypes | Alleles | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Response (n = 109) | Not seizure-free (n = 91) |  | Response A:B; not seizure-free A:B | Odds ratio (95% CI) | P* | ||||||
A/B | AA | AB | BB | AA | AB | BB | p | |||||
SCN1A | rs121918808 | C/T | 108 | 1 | 0 | 90 | 1 | 0 | 1.0000 | 217:1; 181:1 | 0.834 (0.052–13.430) | 1.0000 |
 | rs200176684 | C/T | 108 | 0 | 1 | 91 | 0 | 0 | 1.0000 | 216:2; 182:0 |  | 0.5028 |
 | rs201985242 | G/C | 109 | 0 | 0 | 90 | 1 | 0 | 0.7017 | 218:0; 181:1 |  | 0.4550 |
SCN1B | rs55742440 | T/C | 77 | 29 | 3 | 47 | 35 | 9 | 0.0097 | 183:35; 129:53 | 0.466 (0.287–0.754) | 0.0016 |
 | rs3746255 | C/T | 104 | 4 | 1 | 85 | 6 | 0 | 0.5169 | 212:6; 176:6 | 0.830 (0.263–2.620) | 0.7773 |
 | rs67486287 | G/C | 80 | 27 | 2 | 57 | 28 | 6 | 0.1140 | 187:31; 142:40 | 0.589 (0.351–0.987) | 0.0431 |
 | rs67701503 | C/A | 80 | 27 | 2 | 57 | 28 | 6 | 0.1140 | 187:31; 142:40 | 0.589 (0.351–0.987) | 0.0431 |
 | rs2305748 | C/T | 80 | 27 | 2 | 57 | 28 | 6 | 0.1140 | 187:31; 142:40 | 0.589 (0.351–0.987) | 0.0431 |
 | rs369032304 | G/A | 109 | 0 | 0 | 90 | 1 | 0 | 0.4550 | 218:0; 181:1 |  | 0.4550 |
 | rs72558026 | G/A | 108 | 1 | 0 | 86 | 5 | 0 | 0.0941 | 217:1; 177:5 | 0.163 (0.019–1.409) | 0.0965 |
SCN2A | rs2060198 | T/A | 103 | 5 | 1 | 87 | 3 | 1 | 0.8656 | 211:7; 177:5 | 1.174 (0.366–3.765) | 0.7913 |
 | rs17183814 | G/A | 76 | 30 | 3 | 62 | 27 | 2 | 0.9169 | 182:36; 151:31 | 0.964 (0.569–1.631) | 0.8875 |
 | rs138497939 | A/C | 107 | 2 | 0 | 91 | 0 | 0 | 0.5016 | 216:2; 182:0 |  | 0.5028 |
 | rs185590667 | T/C | 108 | 1 | 0 | 91 | 0 | 0 | 1.0000 | 217:1; 182:0 |  | 1.0000 |
 | rs199925238 | G/A | 108 | 1 | 0 | 91 | 0 | 0 | 1.0000 | 217:1; 182:0 |  | 1.0000 |
 | rs186154973 | G/A | 108 | 1 | 0 | 91 | 0 | 0 | 1.0000 | 217:1; 182:0 |  | 1.0000 |
SCN9A | rs9646771 | T/C | 108 | 1 | 0 | 91 | 0 | 0 | 1.0000 | 217:1; 182:0 | Â | 1.0000 |
 | rs3750904 | T/C | 78 | 26 | 5 | 69 | 20 | 2 | 0.6430 | 182:36; 158:24 | 1.302 (0.745–2.277) | 0.3537 |
 | rs199756028 | G/A | 108 | 1 | 0 | 91 | 0 | 0 | 1.0000 | 217:1; 182:0 |  | 1.0000 |
 | rs200613417 | A/T | 109 | 0 | 0 | 90 | 1 | 0 | 0.4550 | 218:0; 181:1 |  | 0.4550 |
 | rs200956485 | G/A | 108 | 1 | 0 | 91 | 0 | 0 | 1.0000 | 217:1; 182:0 |  | 1.0000 |