Table 3 Characteristics of validated fatigue scales
From: Prevalence and burden of multiple sclerosis-related fatigue: a systematic literature review
Validated fatigue scales | Domains/Components | Range of possible scores | Cut-offs for defining clinically relevant fatigue |
|---|---|---|---|
Fatigue Severity Scale (FSS) | 9 items: activities of daily living, life participation, and sleep | Total: 9–63 Mean of all scores: 1–7 | Total: >  36 [53] |
Fatigue Impact Scale (FIS) | 40 items: physical, cognitive, and social | Total: 0–160  Physical: 0–40  Cognitive: 0–40  Social: 0–80 | Cut-off not reported [9] |
Modified Fatigue Impact Scale (MFIS) | 21 items (full-length) or 5 items (abbreviated): physical, cognitive, and psychosocial functioning | 21-item version: 0–84 (total)  Physical: 0–36  Cognitive: 0–40  Psychosocial: 0–8 5-item version: 0–20 | |
Daily Fatigue Impact Scale (D-FIS) | 8 items: physical, cognitive, and psychosocial | Total: 0–32 | Cut-off not reported [57] |
Fatigue Scale for Motor and Cognitive Functions (FSMC) | 20 items: Cognition and gait | Total: 20-100  Cognitive: 10-50  Physical: 10-50 | Total [58]  Mild fatigue: > 42  Moderate fatigue: > 52  Severe fatigue: > 62 Cognitive  Mild fatigue: > 21  Moderate fatigue: > 27  Severe fatigue: > 33 Physical  Mild fatigue: > 21  Moderate fatigue: > 26  Severe fatigue: > 31 |