Association between hyperpyrexia and poststroke outcomes in patients with recanalization after mechanical thrombectomy: a retrospective cohort study

Table 2 Association between high body temperature levels (BT ≥ 37.5℃) and outcomes

Clinical Outcomes	BT < 37.5℃	BT ≥ 37.5℃	Crude OR (95 %CI)	P value	Adjusted OR^† (95 %CI)	P value^‡
Clinical Outcomes	(n = 106), n (%)	(n = 152), n (%)	Crude OR (95 %CI)	P value	Adjusted OR^† (95 %CI)	P value^‡
Primary outcomes at 3 months
mRS,0–2	48(45.3)	35(23.0)	0.361 (0.211–0.619)	< 0.001	0.384 (0.201–0.733)	0.004
mRS,0–1	33(31.1)	21(13.8)	0.355 (0.191–0.658)	0.001	0.404 (0.200-0.817)	0.012
Secondary outcomes
In-hospital mortality	5(4.7)	24(15.8)	3.787 (1.396–10.277)	0.009	2.796 (0.910–8.593)	0.073
Three-month mortality	18(17.0)	61(40.1)	3.277 (1.795–5.983)	< 0.001	3.087 (1.552–6.135)	0.001
HT	43(40.6)	73(48.0)	1.354 (0.820–2.236)	0.236	1.275 (0.746–2.178)	0.375
HI1	8(7.5)	5(3.3)
HI2	6(5.7)	11(7.2)
PH1	5(4.7)	6(3.9)
PH2	21(19.8)	44(28.9)
SAH/remote HT	3(2.8)	7(4.6)
sICH	15(14.2)	41(27.0)	2.241 (1.166–4.306)	0.015	2.357 (1.176–4.723)	0.016
Early clinical improvement	62(58.2)	41(27.0)	0.262 (0.155–0.444)	< 0.001	0.260 (0.146–0.464)	< 0.001
Early neurological deterioration	13(12.3)	59(38.8)	4.538 (2.332–8.832)	< 0.001	4.780 (2.341–9.871)	< 0.001

Values were measured for the peak body temperature within 24 h following mechanical thrombectomy
Abbreviations: BT body temperature; mRS modified Rankin Scale; OR odds ratio; HT hemorrhage transformation; HI hemorrhagic infarction; SAH subarachnoid hemorrhage; sICH symptomatic intracranial hemorrhage
†The multiple logistic regression test was used to analyze ORs. Adjusted variables: age, sex, length of stay, NIHSS score at baseline, atrial fibrillation, smoking, serum glucose level, SBP, WBC, procedure time, successful reperfusion and number of devices passes
‡The Bonferroni correction method was used to assess the primary and secondary outcomes, and a P value < 0.05/number of comparisons was used as the threshold for statistical significance (P < 0.025 for primary outcomes and P < 0.008 for secondary outcomes)

ISSN: 1471-2377