Table 1 Burden of Multiple Sclerosis in 1990 and 2017 with percentage change by sex and location
From: Burden of multiple sclerosis in Iran from 1990 to 2017
Measure | Unit | Location | Both | Male | Female | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
1990 | 2017 | Percent change c | 1990 | 2017 | Percent change c | 1990 | 2017 | Percent change c | |||
Incidence | Number a | Global | 40,417 (36,731 to 44,787) | 54,895 (50,054 to 60,812) | 35.8 (33.9 to 37.9) | 14,996 (13,560 to 16,691) | 19,930 (18,068 to 22,184) | 32.9 (30.8 to 35.2) | 25,421 (23,138 to 28,110) | 34,964 (31,830 to 38,686) | 37.5 (35.4 to 39.9) |
North Africa and Middle East | 3674 (3240 to 4135) | 7740 (6950 to 8646) | 110.7 (102.5 to 120.3) | 1295 (1133 to 1467) | 2713 (2420 to 3049) | 109.4 (100.8 to 119.2) | 2379 (2102 to 2681) | 5026 (4520 to 5600) | 111.3 (102.5 to 121.6) | ||
Iran | 1122 (1004 to 1254) | 2271 (2024 to 2557) | 102.3 (90.3 to 117.1) | 390 (347 to 436) | 794 (705 to 894) | 103.7 (91.5 to 117.8) | 732 (657 to 821) | 1477 (1315 to 1666) | 101.6 (89.3 to 117.3) | ||
Rate b | Global | 0.7 (0.7 to 0.8) | 0.7 (0.6 to 0.8) | −6.1 (−7.1 to −5.1) | 0.6 (0.5 to 0.6) | 0.5 (0.5 to 0.6) | −10.8 (− 11.8 to − 9.7) | 0.93 (0.85 to 1.03) | 0.90 (0.82 to 1.0) | −3.3 (− 4.5 to − 2.0) | |
North Africa and Middle East | 1.1 (1.0 to 1.2) | 1.2 (1.1 to 1.3) | 7.9 (5.5 to 10.4) | 0.8 (0.7 to 0.9) | 0.8 (0.7 to 0.9) | 1.2 (−1.1 to 3.8) | 1.4 (1.3 to 1.6) | 1.6 (1.5 to 1.8) | 12.7 (9.8 to 15.7) | ||
Iran | 2.0 (1.8 to 2.2) | 2.4 (2.1 to 2.7) | 18.5 (16.7 to 20.5) | 1.4 (1.3 to 1.6) | 1.6 (1.5 to 1.8) | 12.3 (10.8 to 14.1) | 2.6 (2.3 to 2.9) | 3.1 (2.8 to 3.5) | 22.5 (19.9 to 25.3) | ||
Prevalence | Number a | Global | 1,048,261 (946,018 to 1,164,731) | 1,761,078 (1,598,226 to 1,947,909) | 68.0 (65.5 to 70.6) | 335,891 (300,256 to 375,033) | 551,872 (498,079 to 614,373) | 64.3 (61.8 to 66.9) | 712,369 (645,599 to 789,379) | 1,209,206 (1,096,303 to 1,336,075) | 69.7 (67.0 to 72.7) |
North Africa and Middle East | 71,262 (62,756 to 80,648) | 201,299 (181,311 to 223,278) | 182.5 (174.6 to 191.9) | 23,645 (20,552 to 26,789) | 65,344 (58,438 to 72,850) | 176.4 (168.2 to 185.8) | 47,617 (41,965 to 53,835) | 135,955 (122,509 to 150,603) | 185.5 (176.7 to 195.2) | ||
Iran | 21,662 (19,342 to 24,342) | 62,397 (55,554 to 69,871) | 188.1 (179.9 to 196.5) | 7304 (6470 to 8182) | 20,102 (17,828 to 22,498) | 175.2 (167.7 to 183) | 14,358 (12,810 to 16,143) | 42,295 (37,748 to 47,790) | 194.6 (185.1 to 204.6) | ||
Rate b | Global | 22.5 (20.3 to 24.9) | 21.7 (19.7 to 24.0) | −3.4 (−4.6 to −2.1) | 14.5 (13.0 to 16.2) | 13.8 (12.4 to 15.3) | −5.0 (−6.1 to − 3.8) | 30.1 (27.3 to 33.4) | 29.3 (26.6 to 32.4) | −2.5 (− 4.0 to −1.0) | |
North Africa and Middle East | 28.9 (25.6 to 32.7) | 35.8 (32.4 to 39.7) | 23.9 (20.6 to 27.5) | 18.7 (16.4 to 21.2) | 22.2 (19.9 to 24.7) | 18.3 (15.1 to 22.2) | 39.6 (35.1 to 44.8) | 50.5 (45.7 to 56.1) | 27.6 (23.9 to 31.5) | ||
Iran | 55.8 (50.1 to 62.5) | 69.5 (62.1 to 77.8) | 24.7 (22.7 to 26.9) | 36.9 (32.8 to 41.5) | 44.5 (39.7 to 49.8) | 20.6 (18.7 to 22.7) | 75.3 (67.6 to 84.5) | 94.9 (85 to 107) | 26.1 (23.4 to 29) | ||
Deaths | Number a | Global | 12,290 (10,793 to 14,420) | 20,655 (17,721 to 22,238) | 68.1 (14.2 to 83.0) | 5115 (4368 to 5869) | 8452 (7123 to 9182) | 65.2 (17.8 to 79.0) | 7175 (6055 to 9009) | 12,203 (10,082 to 13,629) | 70.1 (12.0 to 87.5) |
North Africa and Middle East | 371 (231 to 648) | 1040 (706 to 1263) | 180.0 (53.3 to 257.9) | 170 (107 to 274) | 489 (332 to 558) | 187.7 (67.8 to 271.3) | 202 (121 to 378) | 551 (346 to 738) | 173.5 (44.3 to 254.2) | ||
Iran | 91 (71 to 131) | 290 (205 to 319) | 219.2 (61.1 to 305.8) | 42 (31 to 58) | 133 (89 to 148) | 219.6 (75.8 to 301.5) | 49 (37 to 74) | 157 (111 to 176) | 218.8 (52.5 to 323.4) | ||
Rate b | Global | 0.3 (0.3 to 0.3) | 0.3 (0.2 to 0.3) | −10.1 (−38.8 to −2.3) | 0.2 (0.2 to 0.3) | 0.2 (0.2 to 0.2) | −11.7 (−37.2 to −4.8) | 0.3 (0.3 to 0.4) | 0.3 (0.2 to 0.3) | −9.2 (−39.8 to 0.0) | |
North Africa and Middle East | 0.2 (0.1 to 0.3) | 0.2 (0.1 to 0.2) | 16.2 (−35.8 to 46.7) | 0.2 (0.1 to 0.3) | 0.2 (0.1 to 0.2) | 18.8 (−30.2 to 51.7) | 0.2 (0.1 to 0.3) | 0.2 (0.1 to 0.3) | 14.8 (−39.2 to 47.6) | ||
Iran | 0.3 (0.2 to 0.4) | 0.4 (0.3 to 0.4) | 27.4 (−34.3 to 60.3) | 0.3 (0.2 to 0.4) | 0.3 (0.2 to 0.4) | 28.7 (−28.6 to 61.7) | 0.3 (0.2 to 0.4) | 0.4 (0.3 to 0.4) | 26.9 (−38.1 to 66.1) | ||
DALYs | Number a | Global | 682,944 (586,530 to 811,282) | 1,084,757 (942,878 to 1,237,344) | 58.8 (29.4 to 72.8) | 262,002 (227,634 to 302,473) | 407,529 (354,187 to 459,135) | 55.5 (28.7 to 68.1) | 420,942 (355,788 to 509,258) | 677,228 (579,371 to 780,792) | 60.9 (31.3 to 76.6) |
North Africa and Middle East | 32,940 (24,924 to 46,413) | 90,888 (71,930 to 110,100) | 175.9 (111.4 to 210.6) | 12,541 (9482 to 17,234) | 34,807 (27,434 to 41,382) | 177.5 (111.0 to 219.3) | 20,399 (15,296 to 29,285) | 56,082 (43,493 to 69,772) | 174.9 (111.8 to 210.5) | ||
Iran | 9098 (7244 to 11,463) | 26,183 (21,205 to 31,381) | 187.8 (122 to 222.9) | 3420 (2752 to 4296) | 9725 (7889 to 11,529) | 184.3 (120.4 to 221.1) | 5677 (4448 to 7296) | 16,458 (13,232 to 19,728) | 189.9 (124 to 229.2) | ||
Rate b | Global | 14.8 (12.8 to 17.5) | 13.3 (11.5 to 15.2) | −10.2 (−26.8 to −2.7) | 11.5 (10.0 to 13.2) | 10.1 (8.8 to 11.4) | −11.9 (− 27.5 to −5.4) | 18.0 (15.2 to 21.6) | 16.3 (14.0 to 18.9) | −9.2 (− 25.6 to −0.6) | |
North Africa and Middle East | 13.6 (10.3 to 19.2) | 16.1 (12.8 to 19.6) | 18.3 (−9.9 to 33.2) | 10.3 (7.8 to 14.2) | 12.0 (9.5 to 14.2) | 16.0 (−12.5 to 33.2) | 17.1 (12.8 to 24.4) | 20.6 (16.1 to 25.4) | 20.7 (−7.3 to 35.9) | ||
Iran | 23.7 (18.9 to 29.8) | 29.1 (23.6 to 34.7) | 23.1 (−5.1 to 37.1) | 17.8 (14.4 to 22.5) | 21.8 (17.6 to 25.7) | 22.4 (−5.6 to 38.2) | 29.7 (23.4 to 38.0) | 36.6 (29.4 to 43.9) | 23.4 (−3.9 to 38.9) | ||