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Table 9 Predictors of poor recovery in NMOSD patients by univariate and multivariable Cox proportional hazards models

From: Association of neutrophil-to-lymphocyte ratio (NLR) with the prognosis of first attack neuromyelitis optica spectrum disorder (NMOSD): a retrospective cohort study

Variable

Univariate

Multivariate

HR (95% CI)

P value

HR (95% CI)

P value

Age, years

1.00(0.99,1.02)

0.47

  

Male sex, no. (%)

0.96(0.65,1.42)

0.964

  

Hypertension, no. (%)

1.28(0.78,2.10)

0.329

  

Diabetes, no. (%)

1.40(0.71,2.77)

0.334

  

Initial EDSS

1.12(1.01,1.23)

0.025

1.09(0.99,1.20)

0.094

Anti-AQP4 antibody, no. (%)

1.26(0.83,192)

0.280

  

LETML

0.78(0.47,1.28)

0.318

  

Corticosteroids, no. (%)

1.35(0.43,4.25)

0.609

  

Immunoglobulins, no. (%)

1.03(0.55,1.92)

0.932

  

Immunosuppressants, no. (%)

1.35(0.92,1.98)

0.127

  

NLR

1.06(1.04,1.08)

0.001

1.08(1.04,1.11)

0.001

PLR

1.00(0.99,1.02)

0.001

1.00(0.99,1.02)

0.423

LMR

1.02(0.99,1.04)

0.218

  

DMT

0.74 (0.44,1.25)

0.264

  
  1. EDSS Extended disability status scale, LMR Lymphocyte-to-monocyte technical ratio, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, LETM longitudinally extensive transverse myelitis, AQP4 aquaporin-4, DMT disease-modifying treatment started during the follow-up
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BMC Neurology

ISSN: 1471-2377

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