Skip to main content

Table 2 Comparison of outcomes between the DAPT and argatroban groups

From: Early argatroban and antiplatelet combination therapy in acute non-lacunar single subcortical infarct associated with mild intracranial atherosclerosis

Variable

DAPT group (n = 168)

Argatroban group (n = 136)

P Value

mRS score of 0–1 at 90 days, no. (%)

80(47.6)

101(74.2)

<0.001

END, no. (%)

37(22.0)

10(7.4)

<0.001

Extracerebral bleeding, no. (%)

2(1.1)

3(2.2)

0.48

Total NIHSS score at discharge, Median (IQR)

3(2–6)

2(2–4)

0.04

Motor NIHSS at discharge, Median (IQR)

3(1–5)

2(1–3)

0.03

Sense NIHSS at discharge, Median (IQR)

1(1–2)

1(1–3)

0.57

Ataxia NIHSS at discharge, Median (IQR)

1(1–2)

1(1–2)

0.42

Hospitalization days, mean (SD), d

8.5 ± 1.9

8.0 ± 1.3

0.015

Venous thrombosis, no. (%)

18(10.7%)

8(5.8%)

0.13

APTT at 24 h, mean (SD), s

22.6 ± 3.1

41.5 ± 3.2

<0.001

  1. Abbreviations: mRS modified Rankin Scale, SD standard deviation, IQR interquartile range, NIHSS National Institutes of Health Stroke Scale, END early neurological deterioration, APTT activated partial thromboplastin time