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Table 3 Risk factors for aspirin HRPR

From: Triglyceride glucose index influences platelet reactivity in acute ischemic stroke patients

Characteristics

Non-HRPR (n = 872)

HRPR (n = 130)

P Value

Age (y)

57.0 [50.0–65.0]

58.0 [50.8–66.0]

0.545

Male, n (%)

632 (72.5)

94 (72.3)

0.968

Smoking, n (%)

428 (49.1)

63 (48.5)

0.895

Alcohol intake, n (%)

361 (41.4)

52 (40.0)

0.763

Medical history, n (%)

 History of stroke/TIA

155 (17.8)

35 (26.9)

0.013

 Hypertension

591 (67.8)

87 (66.9)

0.846

 Diabetes mellitus

295 (33.8)

43 (33.1)

0.865

 Hyperlipidemia

99 (11.4)

13 (10.0)

0.648

 Coronary heart disease

77 (8.80)

10 (7.70)

0.667

Laboratory data

 Triglyceride (mmol/L)

3.46 [2.81–4.18]

3.84 [3.09–4.40]

0.001

 Total cholesterol (mmol/L)

1.23 [0.92–1.07]

1.30 [1.02–1.88]

0.141

 HDL-C (mmol/L)

0.92 [0.79–1.07]

0.92 [0.77–1.09]

0.902

 LDL-C (mmol/L)

2.08 [1.49–2.68]

2.33 [1.80–3.00]

0.001

 Creatinine (μmol/L)

72.0 [62.0–85.0]

73.0 [62.8–83.0]

0.763

 eGFR (mL/min/1.73m2)

94.4 [82.5–103]

94.4[80.9–105]

0.891

 Platelet count (×109/L)

211 [177–251]

221 [180–264]

0.060

 PDW (fL)

13.3 [11.8–15.0]

13.3 [11.9–15.1]

0.935

 P-LCR (%)

33.0 [27.3–39.7]

32.1 [27.0–38.3]

0.593

 Fasting glucose (mmol/L)

5.29 [4.84–6.29]

5.55 [5.05–6.75]

0.010

 HbA1c (%)

5.80 [5.50–6.50]

5.90 [5.60–6.80]

0.297

 MA (mm)

62.4 [58.7–66.0]

63.6 [58.2–66.1]

0.337

TyG index quartiles

  

< 0.001

 Q1 (< 2.02)

232 (26.6)

18 (13.8)

 

 Q2 (2.02–2.27)

221 (25.3)

30 (23.1)

 

 Q3 (2.27–2.52)

214 (24.5)

37 (28.5)

 

 Q4 (≥2.52)

205 (23.5)

45 (34.6)

 
  1. Data given as n (%) or median [interquartile range]
  2. Abbreviations: TIA transient ischemic attack, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, eGFR glomerular filtration rate, PDW platelet distribution width, P-LCR platelet large cell ratio, HbAc1 glycosylated hemoglobin A1c, MA maximum amplitude, TyG index triglyceride glucose index, Q1–Q4 TyG index quartiles