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Table 3 Risk factors for aspirin HRPR

From: Triglyceride glucose index influences platelet reactivity in acute ischemic stroke patients

Characteristics Non-HRPR (n = 872) HRPR (n = 130) P Value
Age (y) 57.0 [50.0–65.0] 58.0 [50.8–66.0] 0.545
Male, n (%) 632 (72.5) 94 (72.3) 0.968
Smoking, n (%) 428 (49.1) 63 (48.5) 0.895
Alcohol intake, n (%) 361 (41.4) 52 (40.0) 0.763
Medical history, n (%)
 History of stroke/TIA 155 (17.8) 35 (26.9) 0.013
 Hypertension 591 (67.8) 87 (66.9) 0.846
 Diabetes mellitus 295 (33.8) 43 (33.1) 0.865
 Hyperlipidemia 99 (11.4) 13 (10.0) 0.648
 Coronary heart disease 77 (8.80) 10 (7.70) 0.667
Laboratory data
 Triglyceride (mmol/L) 3.46 [2.81–4.18] 3.84 [3.09–4.40] 0.001
 Total cholesterol (mmol/L) 1.23 [0.92–1.07] 1.30 [1.02–1.88] 0.141
 HDL-C (mmol/L) 0.92 [0.79–1.07] 0.92 [0.77–1.09] 0.902
 LDL-C (mmol/L) 2.08 [1.49–2.68] 2.33 [1.80–3.00] 0.001
 Creatinine (μmol/L) 72.0 [62.0–85.0] 73.0 [62.8–83.0] 0.763
 eGFR (mL/min/1.73m2) 94.4 [82.5–103] 94.4[80.9–105] 0.891
 Platelet count (×109/L) 211 [177–251] 221 [180–264] 0.060
 PDW (fL) 13.3 [11.8–15.0] 13.3 [11.9–15.1] 0.935
 P-LCR (%) 33.0 [27.3–39.7] 32.1 [27.0–38.3] 0.593
 Fasting glucose (mmol/L) 5.29 [4.84–6.29] 5.55 [5.05–6.75] 0.010
 HbA1c (%) 5.80 [5.50–6.50] 5.90 [5.60–6.80] 0.297
 MA (mm) 62.4 [58.7–66.0] 63.6 [58.2–66.1] 0.337
TyG index quartiles    < 0.001
 Q1 (< 2.02) 232 (26.6) 18 (13.8)  
 Q2 (2.02–2.27) 221 (25.3) 30 (23.1)  
 Q3 (2.27–2.52) 214 (24.5) 37 (28.5)  
 Q4 (≥2.52) 205 (23.5) 45 (34.6)  
  1. Data given as n (%) or median [interquartile range]
  2. Abbreviations: TIA transient ischemic attack, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, eGFR glomerular filtration rate, PDW platelet distribution width, P-LCR platelet large cell ratio, HbAc1 glycosylated hemoglobin A1c, MA maximum amplitude, TyG index triglyceride glucose index, Q1–Q4 TyG index quartiles